Main Article Content
Abstract
Ethosomes are a novel class of bilayer lipid vesicles that improve the penetration of hydrophilic and lipophilic medications via the skin and systemic circulation by facilitating their transdermal administration. The formulation, preparation techniques, and different ethosome types classical, binary, and transethosomes are reviewed in this study, with an emphasis on their composition and the function of penetration enhancers. Using a variety of characterisation approaches, the mechanisms behind drug penetration are examined, with a focus on the effects of ethanol and the structural features of ethosomes. The paper also lists currently available ethosomal products on the market and talks about potential future uses for them in therapeutic contexts, such as non-invasive vaccination delivery and chronic illness therapy. All things considered, ethosomes offer a viable way to improve drug delivery systems, with major advantages for pharmaceutical applications.