Main Article Content
Abstract
Organogel are semi- soild system in which a three - dimensional network of self assembled, interlaced gelator fibres immobilizers an organic liquid phase. Unfortunately, the toxicity of the selected organic solvents has impeded their usage as medication delivery methods in the past.
Although transdermal drug delivery systems (DDS) offer numerous benefits for patients including the avoidance of both gastric irritation and first pass metabolism effect, as well as improved patient compliance, only active ingredients. The hard gelatin capsules is the most versatile of all dosage forms capsule are soild dosage contains two pieces as it consists of two pieces is small cylinders closed. The administration of liquid and soild drugs enclosed hard gelatin capsule one of the most frequent utilzed dosage forms.
The study investigates kneaf core drying uniformity in a tray dryer through computational fluid dynamics simulation. However the greatest draw back of the tray dryer is uneven drying because of poor air flow distribution in the drying chamber implementing the property design of tray dryer system may eliminate or reduce non uniformity of drying and increase dryer efficiency.
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References
- 1. Almeida. Moisturizing effect of hydrogels mixtures pharmaceutical development and technology. 2022;3(9):487-94.
- 2. chu. The low cost drying methods for developing countries trend in food science technology. 2014;67(14):519-28.
- 3. Anthanasions. Optimal control of a freeze dryer theretical development and quasi- steady state and reasearch chemical engineering sciences. 2012;34(7):975-8.
- 4. Davidson. Transdermal drug delivery by coated microneedles geometry effects on skin thickness and drug permeability. Vol. 2010(86):(98)119-1206.
- 5. Bahubali Equipment qualification of anew laboratory tray dryer in pharmacy technology2013;12;2:805-88.
- 6. Farias. Thethree dimensional (3D) printing microneedles cell extrusion bioengineering. 2008;78(544):425-32.
- 7. Haj- Ahmad microneedles coating technique for transdermal drug delivery. 2015;76:486-502.
- 8. Caudill. The spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery. 2007;9(284):122-32.
- 9. Mujawar. Organogels: factors and it’s importance. Int J Pharm Chem Biol Sci. 2014;4(3):758-73.
- 10. Cronin. The development of a simulation tool to enable optimisation of the energy consumption of the industrial timber – drying process applied energy. 2011;75(53):325-40.
- 11. Alsaaborganogels in drug delivery a special emphasis on pluronic lectin organogels in pharmaceutical sciences. 2000;15(4):592-605.
- 12. Dionissios. Thedried product quality improvement by airflow manipulation in tray dryer. 2001;101(89):401-678.
- 13. Bennamoun design and simulation of a solar dryer for agriculture products. 2019;59(12):259-87.
- 14. El-sayed. The fast separable microneedles prepared with the aid of 3D printing for nanoparticles delivery. 2018;34(87):166-74.
- 15. Bariy. The microneedle an emerging transdermal drug2014;65;76:11-78.
- 16. Gupta. The kinetics of skin realising after insertion of injection of microneedles in humans. 2005;154(546):120-47.
- 17. Brown. The transdermal drug delivery systems skin perturbation devices. 2016;43(57):119-39.
- 18. Mahmoud A spray drying of biopharmaceutical stability and process consideration. Taylor and Francis online. 2006; 24;6:763-8.
- 19. Corium. The system utilizes dissolving microstructure (microneedles) for innovative needle for free delivery across skin.2014;98(678):187-876.
- 20. Mishra. Feasibility studies on Nafion member Actuatef micropupm integrated with hallow microneedles for insulin delivery devices. Vol. 28(4):(987-996; 2019.
References
1. Almeida. Moisturizing effect of hydrogels mixtures pharmaceutical development and technology. 2022;3(9):487-94.
2. chu. The low cost drying methods for developing countries trend in food science technology. 2014;67(14):519-28.
3. Anthanasions. Optimal control of a freeze dryer theretical development and quasi- steady state and reasearch chemical engineering sciences. 2012;34(7):975-8.
4. Davidson. Transdermal drug delivery by coated microneedles geometry effects on skin thickness and drug permeability. Vol. 2010(86):(98)119-1206.
5. Bahubali Equipment qualification of anew laboratory tray dryer in pharmacy technology2013;12;2:805-88.
6. Farias. Thethree dimensional (3D) printing microneedles cell extrusion bioengineering. 2008;78(544):425-32.
7. Haj- Ahmad microneedles coating technique for transdermal drug delivery. 2015;76:486-502.
8. Caudill. The spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery. 2007;9(284):122-32.
9. Mujawar. Organogels: factors and it’s importance. Int J Pharm Chem Biol Sci. 2014;4(3):758-73.
10. Cronin. The development of a simulation tool to enable optimisation of the energy consumption of the industrial timber – drying process applied energy. 2011;75(53):325-40.
11. Alsaaborganogels in drug delivery a special emphasis on pluronic lectin organogels in pharmaceutical sciences. 2000;15(4):592-605.
12. Dionissios. Thedried product quality improvement by airflow manipulation in tray dryer. 2001;101(89):401-678.
13. Bennamoun design and simulation of a solar dryer for agriculture products. 2019;59(12):259-87.
14. El-sayed. The fast separable microneedles prepared with the aid of 3D printing for nanoparticles delivery. 2018;34(87):166-74.
15. Bariy. The microneedle an emerging transdermal drug2014;65;76:11-78.
16. Gupta. The kinetics of skin realising after insertion of injection of microneedles in humans. 2005;154(546):120-47.
17. Brown. The transdermal drug delivery systems skin perturbation devices. 2016;43(57):119-39.
18. Mahmoud A spray drying of biopharmaceutical stability and process consideration. Taylor and Francis online. 2006; 24;6:763-8.
19. Corium. The system utilizes dissolving microstructure (microneedles) for innovative needle for free delivery across skin.2014;98(678):187-876.
20. Mishra. Feasibility studies on Nafion member Actuatef micropupm integrated with hallow microneedles for insulin delivery devices. Vol. 28(4):(987-996; 2019.