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Abstract
Gastric cancer (GC) is a major global health problem and ranks among the most frequently diagnosed and most deadly cancers, causing over 770,000 deaths in 2025. Gastric cancer is a common and highly lethal malignancy worldwide. Its incidence is higher in many Asian and less developed regions and is associated with both modifiable and non‑modifiable risk factors, including Helicobacter pylori infection, poor diet, smoking, older age, and low socioeconomic status. Prevention strategies focus on H. pylori eradication, lifestyle modification, and appropriate use of screening programs where incidence is high. Several classification systems, such as those from the World Health Organization and Lauren, guide GC staging and incorporate anatomical, histological, and increasingly molecular characteristics. This review provides an overview of Gastric Cancer including its Introduction, Epidemiology, Risk factors, Prevention, Symptoms, Diagnosis, Treatment. Symptoms are often nonspecific such as weight loss, anemia, abdominal pain, dysphagia, and gastrointestinal bleeding so diagnosis typically relies on upper gastrointestinal endoscopy with biopsy, supported by imaging techniques like computed tomography and endoscopic ultrasound. Surgery with adequate lymph node dissection remains the cornerstone of curative treatment, while chemotherapy, chemoradiotherapy, and targeted or immunotherapies are used in a multimodal approach to improve survival in appropriate patients.