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Jan 6, 2025
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Jan 6, 2025
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Abstract

Trigonella foenum graecum leaves have been used as antidiabetic remedies in many cultures for thousands of years. The aim of this review is to address the existing evidence on antidiabetic effects of the Trigonella foenum graecum. The hypoglycaemic effects, antidyslipidaemics, antioxidative effects and the safety of the Trigonella foenum graecum leaves have been scientifically validated by using in vitro and in vivo studies. Multiple cell regeneration, insulin b mechanisms responsible for hypoglycaemic effects of Trigonella foenum graecum including release and insulin like actions of some compounds isolated were identified. Epicatechin, a cell regeneration and b flavonoid isolated from the leaves has shown insulin-like effects, effects on insulin release. Several compounds including pterostilbene and marsupsin isolated from the Trigonella foenum graecum leaves were identified as compounds with hypoglycaemic effects.Few investigations focused on the antidiabetic effects of Trigonella foenum graecum latex have demonstrated strong inhibitory effects of the latex on α-amylase and α-glucosidase activities and on protein glycation. Investigations focusing on the antidiabetic effects and possible toxicity of the Trigonella foenum graecum are essential to validate its efficacy and safety.

Keywords

Anti diabetic Neuropathy,diabetes Trigonella foenum graecum etc

Article Details

How to Cite
T. Sai Kishore, J. Amos babu, & K. Anupama Priyadarshini. (2025). Evaluation of Antidiabetic Activity Of Trigonella Foenum Graecum Leaves In Alloxan Induced Type-II Diabetis. International Journal of Research in Pharmacology & Pharmacotherapeutics, 14(1), 1-10. Retrieved from https://ijrpp.com/ijrpp/article/view/609
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