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Dec 23, 2024
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Dec 23, 2024
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Abstract

Wrightia tinctoria R. Br. belongs to the family Apocynaceae, commonly called Sweet Indrajao, Pala Indigo Plant, and Dyer's Oleander. “Jaundice curative tree” in south India. Sweet Indrajao is a small, deciduous tree with a light gray, scaly, smooth bark. Native to India and Burma, Wrightia is named after a Scottish physician and botanist, William Wright (1740–1827). Sweet Indrajao is called dhudi (Hindi) because of its preservative nature. The juice of the tender leaves is used effectively in jaundice. Crushed fresh leaves, when filled in the cavity of a decayed tooth, relieve toothache. In the Siddha system of medicine, it is used for psoriasis and other skin diseases. In the current investigation,WTET extract has shown anti-inflammatory and antioxidant properties. WTET Oil extract has shown significant in vitro antioxidant activity by DPPH assay in the current investigation. At 100 mg/ml WTET, the average inhibition percentage is 80.5%, with the IC50 value found to be 86.1861 mg/ml compared to the standard ascorbic acid IC50 value of 33.7334 mg/ml. Further investigation of in vitro anti-inflammatory activity by the protein denaturation method compared to the standard. At 300 mg/ml, WTET has an average inhibition percentage of 47.6%, with the IC50 value found to be 326.2789 mg/ml compared to the standard IC50 value of 121.29 mg/ml. Overall investigation results, such as WTET, had good antioxidant and moderate anti-inflammatory activity. WT ET also investigate with invitro antimicrobial activity against human pathogenic microbes  causes skin infection as a result significant compared to standard

Keywords

Wrightia tinctoria antioxidant anti-inflammatory and antimicrobial DPPH assay

Article Details

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P. Selvam. (2024). Invitro Antioxidant activity, Anti-inflammatory and Antimicrobial activity of Wrightia tinctoria. International Journal of Research in Pharmacology & Pharmacotherapeutics, 13(4), 705-713. Retrieved from https://ijrpp.com/ijrpp/article/view/606
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References

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