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Abstract

Caesalpinia pulcherrima. Belongs to the family Fabaceae. Depressions are widespread psychiatric disorders affecting around 5% of the population. Furthermore, it is difficult to predict which patient will respond to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. The present study was designed to evaluate the antidepressant activity of the alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves in rodents. The antidepressant activity was tested by using forced swim test and Open Field Test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves having antidepressant activity. Alcoholic extract of Caesalpinia pulcherrima leaves showing more significant activity over the aqueous extract

Keywords

Caesalpinia pulcherrima Antidepressant activity forced swim test Open Field Test

Article Details

How to Cite
R. Harshitha, P. Udaya Chandrika, A. Srinivasa Rao, AV. Kishore Babu, & P. Sobitha Rani. (2024). Pharmacological Evaluation Of Anti Depressant Activity Of Caesalpinia Pulcherrima In Animal Models. International Journal of Research in Pharmacology & Pharmacotherapeutics, 13(4), 556-565. Retrieved from https://ijrpp.com/ijrpp/article/view/589

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