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Abstract
Caesalpinia pulcherrima. Belongs to the family Fabaceae. Depressions are widespread psychiatric disorders affecting around 5% of the population. Furthermore, it is difficult to predict which patient will respond to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. The present study was designed to evaluate the antidepressant activity of the alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves in rodents. The antidepressant activity was tested by using forced swim test and Open Field Test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves having antidepressant activity. Alcoholic extract of Caesalpinia pulcherrima leaves showing more significant activity over the aqueous extract
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References
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- 2. Abayomi, S (1993). Historical review of traditional medicine in Africa, Spectrum Book ltd pp: 9-25. Ibadan.
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- 6. Baker, J.E., Brotz. H., Leichert, L.I.O., Labischinski, H and Hecker, M (2003). Proteomic approach to understanding antibiotic action, Antimicro. Agents. Chemotherapy 47: 948-955.
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- 9. Rabe T, Staden JV (1997): Antibacterial activity of South African plants used for medicinal purposes. J. Ethnopharmacol. 56: 81-87.
- 10. Kamboj VP (2000): Herbal medicine. Cur. Sc. 78(1): 35-39.
- 11. Ghani, A. (1998). Medicinal Plants of Bangladesh: Chemical Constituents and Uses. Asiatic Society of Bangladesh, Dhaka.
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- 13. Chatterjee, I. Chakravarty, A.K., Gomesa A., (2006) Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus R.Br . Journal of Ethnopharmacology 106(1), 38-43.
- 14. Ramadan, Mohammad A., and N. A. Safwat. Antihelicobacter activity of a flavonoid compound isolated from Desmostachya bipinnata. Australian Journal of Basic & Applied Sciences 3.3 (2009): 2270-2277.
- 15. Kumar, K. Ashok, et al. Chemical composition and antimicrobial activity of the essential oil of Desmostachya bipinnata linn." International Journal of Phytomedicine 2.4 (2011).
- 16. Gupta, S. R., and J. S. Singh. "Soil respiration in a tropical grassland. Soil Biology and Biochemistry 13.4 (1981): 261-268.
- 17. Rao, D. L. N., and S. K. Ghai. "Urease and dehydrogenase activity of alkali and reclaimed soils." Soil Research 23.4 (1985): 661-665.
- 18. Gulzar, Salman, M. A. Khan, and Xiaojing Liu. Seed germination strategies of Desmostachya bipinnata: a fodder crop for saline soils. Rangeland Ecology & Management 60.4 (2007): 401-407.
- 19. Bajwa, Rukhsana, et al. Antifungal activity of allelopathic plant extracts II: In vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses. Integrated plant disease management. Proceedings of 3rd National Conference of Plant Pathology, NARC, Islamabad, 1-3 Oct. 2001. Pakistan Phytopathology Society, 2002.
- 20. Shrestha, Sabina, et al. "Sterols from the leafy culms of Desmostachya bipinnata." Chemistry of Natural Compounds 47.5 (2011): 852-853.
References
1. Sofowora, A., 1982, Medicinal Plants and Traditional Medicine in Africa, John Wiley and Sons Ltd., Chichester. New York. Toronto. Singapore, pages 6,10,11,74,114,256.
2. Abayomi, S (1993). Historical review of traditional medicine in Africa, Spectrum Book ltd pp: 9-25. Ibadan.
3. Herborn, J.B (1998). Phytochemical methods, A guide to modern techniques of plant analysis, pp. 5-11, 2nd edition.
4. Colombo, M.L and Bosisio, E (1996). Pharmacological activites of chelidonium majus L (papveraceae), Pharmacol. Res 33: 127-134.
5. El-seedi, H.R., Ohara, T., Sata, N. and Nishiyama, S (2002). Antimicrobial terpenoids from Eupatorium glutinosum (Asteraceae), J. Ethnopharmacol 81:293-296.
6. Baker, J.E., Brotz. H., Leichert, L.I.O., Labischinski, H and Hecker, M (2003). Proteomic approach to understanding antibiotic action, Antimicro. Agents. Chemotherapy 47: 948-955.
7. Levetin and McMahon, (2003), Plants and Society, 3rd edition.
8. Chopra, R.N., Nayar, S.L. and Chopra, I.C. (1956) In Glossary of Indian medicinal plants, Vol. I. Council of Scientific and Industrial Research, New Delhi, pp. 197.
9. Rabe T, Staden JV (1997): Antibacterial activity of South African plants used for medicinal purposes. J. Ethnopharmacol. 56: 81-87.
10. Kamboj VP (2000): Herbal medicine. Cur. Sc. 78(1): 35-39.
11. Ghani, A. (1998). Medicinal Plants of Bangladesh: Chemical Constituents and Uses. Asiatic Society of Bangladesh, Dhaka.
12. Farnsworth, N.R., Akerele, O., Medicinal plants in therapy. Bull. World Health. Org.. v.63, n.6, p.965-981, 1985.
13. Chatterjee, I. Chakravarty, A.K., Gomesa A., (2006) Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus R.Br . Journal of Ethnopharmacology 106(1), 38-43.
14. Ramadan, Mohammad A., and N. A. Safwat. Antihelicobacter activity of a flavonoid compound isolated from Desmostachya bipinnata. Australian Journal of Basic & Applied Sciences 3.3 (2009): 2270-2277.
15. Kumar, K. Ashok, et al. Chemical composition and antimicrobial activity of the essential oil of Desmostachya bipinnata linn." International Journal of Phytomedicine 2.4 (2011).
16. Gupta, S. R., and J. S. Singh. "Soil respiration in a tropical grassland. Soil Biology and Biochemistry 13.4 (1981): 261-268.
17. Rao, D. L. N., and S. K. Ghai. "Urease and dehydrogenase activity of alkali and reclaimed soils." Soil Research 23.4 (1985): 661-665.
18. Gulzar, Salman, M. A. Khan, and Xiaojing Liu. Seed germination strategies of Desmostachya bipinnata: a fodder crop for saline soils. Rangeland Ecology & Management 60.4 (2007): 401-407.
19. Bajwa, Rukhsana, et al. Antifungal activity of allelopathic plant extracts II: In vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses. Integrated plant disease management. Proceedings of 3rd National Conference of Plant Pathology, NARC, Islamabad, 1-3 Oct. 2001. Pakistan Phytopathology Society, 2002.
20. Shrestha, Sabina, et al. "Sterols from the leafy culms of Desmostachya bipinnata." Chemistry of Natural Compounds 47.5 (2011): 852-853.