Main Article Content
Abstract
Delonix Regia Belongs to the family Fabaceae. Depressions are widespread psychiatric disorders affecting around 5% of the population. Furthermore, it is difficult to predict which patient will respond to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. The present study was designed to evaluate the antidepressant activity of the alcoholic and aqueous extracts of Delonix Regia leaves in rodents. The antidepressant activity was tested by using forced swim test and Open Field Test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that alcoholic and aqueous extracts of Delonix Regia leaves having antidepressant activity. Alcoholic extract of Delonix Regia leaves showing more significant activity over the aqueous extract.
Keywords
Article Details
References
- 1. Sofowora A. Medicinal plants and traditional medicine in Africa. Chichester: John Wiley & Sons Ltd.; 1982. New York. Toronto. Singapore;74(114),256:6, 10, 11.
- 2. Abayomi S. Historical review of traditional medicine in Africa, Spectrum Book Ltd pp. Ibadan; 1993. p. 9-25.
- 3. Herborn JB. Phytochemical methods, A guide to modern techniques of plant analysis. 2nd ed; 1998. p. 5-11.
- 4. Colombo ML, Bosisio E. Pharmacological activities of Chelidonium majus L. (papveraceae). Pharmacol Res. 1996;33(2):127-34. doi: 10.1006/phrs.1996.0019, PMID 8870028.
- 5. El-Seedi HR, Ohara T, Sata N, Nishiyama SAntimicrobial diterpenoids from Eupatorium glutinosum (Asteraceae). J Ethnopharmacol. 2002;81(2):293-6. doi: 10.1016/s0378-8741(02)00101-0, PMID 12065166.
- 6. Baker JE, Brotz H, Leichert LIO, Labischinski H, Hecker M. Proteomic approach to understanding antibiotic action, Antimicro. Agents Chemother. 2003;47:948-55.
- 7. Levetin, McMahon. Plants and society. 3rd ed; 2003.
- 8. Chopra RN, Nayar SL, Chopra IC. In Glossary of Indian medicinal plants. Vol. I. New Delhi: Council of Scientific and Industrial Research; 1956. p. 197.
- 9. Rabe T, van Staden JV. Antibacterial activity of South African plants used for medicinal purposes. J Ethnopharmacol. 1997;56(1):81-7. doi: 10.1016/s0378-8741(96)01515-2, PMID 9147258.
- 10. Kamboj VP. Herbal medicine. Curr Sci. 2000;78(1):35-9.
- 11. Ghani A. Medicinal plants of Bangladesh: chemical constituents and uses. Dhaka: Asiatic Society of Bangladesh; 1998.
- 12. Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z. Medicinal plants in therapy. Bull World Health Organ. 1985;63(6):965-81. doi: 10.1016/0378-8741(87)90016-X, PMID 3879679.
- 13. Chatterjee I, Chakravarty AK, Gomes A. Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus R.Br. J Ethnopharmacol. 2006;106(1):38-43. doi: 10.1016/j.jep.2005.11.031, PMID 16426782.
- 14. Ramadan MA, Safwat NA. Antihelicobacter activity of a flavonoid compound isolated from Desmostachya bipinnata. Aust J Basic Appl Sci. 2009;3(3):2270-7.
- 15. Kumar KA, et al. Chemical composition and antimicrobial activity of the essential oil of Desmostachya bipinnata linn. Int J Phytomed. 2011:2.4.
- 16. Gupta SR, Singh JS. Soil respiration in a tropical grassland. Soil Biol Biochem. 1981;13(4):261-8. doi: 10.1016/0038-0717(81)90060-2.
- 17. Rao DLN, Ghai SK. Urease and dehydrogenase activity of alkali and reclaimed soils. Soil Res. 1985;23(4):661-5. doi: 10.1071/SR9850661.
- 18. Gulzar S, Khan MA, Liu X. Seed germination strategies of Desmostachya bipinnata: a fodder crop for saline soils. Rangeland Ecol Manag. 2007;60(4):401-7. doi: 10.2111/1551-5028(2007)60[401:SGSODB]2.0.CO;2.
- 19. Bajwa R, et al. Antifungal activity of allelopathic plant extracts II: in vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses Integrated plant disease management. Proceedings of the 3rd national conference of plant pathology, narc, Islamabad. Oct 1-3 2001.. Pakistan Phytopathology Society;2002.
- 20. Shrestha S, Lyu H, Park J, Lee D, Cho JG, Cui E, et al. Sterols from the leafy culms of Desmostachya bipinnata. Chem Nat Compd. 2011;47(5):852-3. doi: 10.1007/s10600-011-0083-2.
References
1. Sofowora A. Medicinal plants and traditional medicine in Africa. Chichester: John Wiley & Sons Ltd.; 1982. New York. Toronto. Singapore;74(114),256:6, 10, 11.
2. Abayomi S. Historical review of traditional medicine in Africa, Spectrum Book Ltd pp. Ibadan; 1993. p. 9-25.
3. Herborn JB. Phytochemical methods, A guide to modern techniques of plant analysis. 2nd ed; 1998. p. 5-11.
4. Colombo ML, Bosisio E. Pharmacological activities of Chelidonium majus L. (papveraceae). Pharmacol Res. 1996;33(2):127-34. doi: 10.1006/phrs.1996.0019, PMID 8870028.
5. El-Seedi HR, Ohara T, Sata N, Nishiyama SAntimicrobial diterpenoids from Eupatorium glutinosum (Asteraceae). J Ethnopharmacol. 2002;81(2):293-6. doi: 10.1016/s0378-8741(02)00101-0, PMID 12065166.
6. Baker JE, Brotz H, Leichert LIO, Labischinski H, Hecker M. Proteomic approach to understanding antibiotic action, Antimicro. Agents Chemother. 2003;47:948-55.
7. Levetin, McMahon. Plants and society. 3rd ed; 2003.
8. Chopra RN, Nayar SL, Chopra IC. In Glossary of Indian medicinal plants. Vol. I. New Delhi: Council of Scientific and Industrial Research; 1956. p. 197.
9. Rabe T, van Staden JV. Antibacterial activity of South African plants used for medicinal purposes. J Ethnopharmacol. 1997;56(1):81-7. doi: 10.1016/s0378-8741(96)01515-2, PMID 9147258.
10. Kamboj VP. Herbal medicine. Curr Sci. 2000;78(1):35-9.
11. Ghani A. Medicinal plants of Bangladesh: chemical constituents and uses. Dhaka: Asiatic Society of Bangladesh; 1998.
12. Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z. Medicinal plants in therapy. Bull World Health Organ. 1985;63(6):965-81. doi: 10.1016/0378-8741(87)90016-X, PMID 3879679.
13. Chatterjee I, Chakravarty AK, Gomes A. Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus R.Br. J Ethnopharmacol. 2006;106(1):38-43. doi: 10.1016/j.jep.2005.11.031, PMID 16426782.
14. Ramadan MA, Safwat NA. Antihelicobacter activity of a flavonoid compound isolated from Desmostachya bipinnata. Aust J Basic Appl Sci. 2009;3(3):2270-7.
15. Kumar KA, et al. Chemical composition and antimicrobial activity of the essential oil of Desmostachya bipinnata linn. Int J Phytomed. 2011:2.4.
16. Gupta SR, Singh JS. Soil respiration in a tropical grassland. Soil Biol Biochem. 1981;13(4):261-8. doi: 10.1016/0038-0717(81)90060-2.
17. Rao DLN, Ghai SK. Urease and dehydrogenase activity of alkali and reclaimed soils. Soil Res. 1985;23(4):661-5. doi: 10.1071/SR9850661.
18. Gulzar S, Khan MA, Liu X. Seed germination strategies of Desmostachya bipinnata: a fodder crop for saline soils. Rangeland Ecol Manag. 2007;60(4):401-7. doi: 10.2111/1551-5028(2007)60[401:SGSODB]2.0.CO;2.
19. Bajwa R, et al. Antifungal activity of allelopathic plant extracts II: in vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses Integrated plant disease management. Proceedings of the 3rd national conference of plant pathology, narc, Islamabad. Oct 1-3 2001.. Pakistan Phytopathology Society;2002.
20. Shrestha S, Lyu H, Park J, Lee D, Cho JG, Cui E, et al. Sterols from the leafy culms of Desmostachya bipinnata. Chem Nat Compd. 2011;47(5):852-3. doi: 10.1007/s10600-011-0083-2.