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Abstract
Aim: The purpose of the current study was to assess the anti-psoriatic properties of ointments containing hydro-alcoholic extract of Cassia auriculata leaves at 1% and 2% (w/w).
Introduction: Ointments are preparations that are homogeneous, transparent, viscous, and semi-solid and are applied externally to the skin or mucous membranes. The plant Cassia auriculata L., a member of the Leguminosae family of plants, is used in the Ayurvedic medical system to cure leprosy, diabetes, and other skin conditions. A persistent, inflammatory skin condition that affects millions of individuals worldwide is psoriasis.
Materials and Methods: Because of their ability to alter the immune system and lessen inflammation, natural ingredients have drawn attention as a psoriasis treatment. Wool fat, hard paraffin, Ceto-stearyl alcohol, and white soft paraffin were used to make a herbal ointment for psoriasis.
Results: The produced ointments' physical properties were evaluated, and the findings were satisfactory and the consistency was suitable for application.
Conclusion: Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide. The use of natural products to treat psoriasis has gained interest due to their ability to modulate the immune system and reduce inflammation. Traditional medicinal plants of India represent a promising source of natural products for the treatment of psoriasis.
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References
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References
1. Schmidt JE. Medical discoveries, who and when. Springfield, IL: Thomas; 1959:391.
2. McClelland PB. New treatment options for psoriasis. Dermatol Nurs. 1997; 9:295-304.
3. National Psoriasis Foundation. Psoriasis statistics. www.psoriasis.or/stat.html (accessed 1999 Feb 22).
4. Ortonne JP. Aetiology and pathogenesis of psoriasis. Br J Dermatol. 1996; 135(suppl 49):1-5.
5. Duvic M, Nagpal S, Asano AT et al. Molecular mechanisms of tazarotene action in psoriasis. J Am Acad Dermatol. 1997; 37(2, part 3): S18- 24
6. Mahrle G, Bonnekoh B, Wevers A et al. Anthralin: how does it act and are there more favourable derivatives? Acta Derm Venereol. 1994; 74(suppl 186):83-4.
7. Dassanayake MD, Fosberg FR. A Revised Handbook to the Flora of Ceylon- Complete Set. Taylor and Francis US; 1980 Jun 1.
8. Dassanayake, M.D. and Fosberg, F.R. A Revised Handbook to the Flora of Ceylon. 1981. (Vol. II). Smithsonian Institution and National Science Foundation, Washington D.C., Amerind Publishing Co Pvt Ltd, New Delhi.
9. Malmstrom, Ivar. Technological aspects of lanolin. Journal of Cosmetic. 1949; 1(4). Archived from the original on 4 November 2021.
10. Record in the GESTIS Substance Database of the GESTIS Substance DatabaseInstitute for Occupational Safety and HealthRecord.
11. Cetostearyl alcohol in the Consumer Product Information Database.
12. Petrolatum (white). inchem.org. International Programme on Chemical Safety and the Commission of the European Communities. March 2002. Retrieved 5 August 2011.