Preparation And Evaluation Of Herbal Ointment For Treatment Of Skin Infection

Abstract

1. procumbens is found along roadsides, waste grounds, dikes, railroads, riverbanks, meadows, and dunes. Its widespread distribution and importance as a weed are due to its spreading stems and abundant seed production. Leaves are simple, opposite, stipulate, Phytochemical screening revealed the existence of flavonoids, alkaloids, carotenoids, b-sitisterol, n-hexane, fumaric acid, luteolin, glucoluteolin, quercetin, isoquercetin, dexamethasone, lauric acid, rutin, palmitic, myristic, linoleic acid, arachidic, tannins and oxoester. A novel flavonoid named ‘procumbenetin’ has been extracted from the leaf of the plant. Turmeric is the dried rhizome of Curcuma longaLinn isolation of curcuminoids Method: The extract was obtained by the maceration method with 90% ethanol. Simple ointment IP was use as ointment base for dispersion of the plant extract parameter investigated includes spreadability, pH and viscosity of extract. Result: Dry leave of part of plant powder and extract by maceration technique of extraction with ethanol and isolated curcumin. The pH of ointment was 6.06 ± 6.10 and the spreadability was 45 ± 48mm slightly washable and non irritant viscous in nature, insoluble in water, soluble in ether and chloroform, no pink colour from the rancidity test are passed and loss on drying is passed. Conclusion: T. procumbens ethanol extract has a good therapeutic value for combating tropical infection disease. The Turmeric, T. procumbens combined ointment is used as a potential agent for treatment of skin infection.