Anti-Amnesic Potential of Artabotrys hexapetalus: Phytochemical Insights and Pharmacological Perspectives

Abstract

Artabotrys hexapetalus (L.f.) Bhandari, a medicinal climber of the Annonaceae family, is traditionally valued for its memory enhancing and therapeutic properties. Its leaves, flowers and essential oils are rich in alkaloids, flavonoids, terpenoids and compounds such as kaempferol and quercetin many of which are associated with neuroprotective and amnesic effects in other botanicals. Pharmacological studies confirm diverse activities, including antioxidant, anti-inflammatory, hepatoprotective and antimicrobial effects which indirectly support neurological health. Although direct evidence for amnesic efficacy remains limited traditional usage as a relaxant and the presence of bioactive molecules that modulate neurotransmitter pathways suggest promising anti-amnesic potential. Essential flavonoid constituents are particularly significant given their role in memory enhancing for learning and improving cognitive functions. Future research should focus on in vivo and clinical validation of amnesic effects, along with mechanistic studies to establish A. hexapetalus as a natural candidate for managing amnesic disorders.