Main Article Content
Abstract
Background
Studies on prescription pattern have important value in the health set up and eventually provides insight into the efficiency of drug use and results of such research studies can be helpful to set priorities for the rational and effective use of medicines. Acute Myocardial Infarction (MI) is the main Congestive Heart Disease which has high morbidity and mortality and despite having the specific guidelines of treatment various drug therapy is still underused so study on prescription pattern of drugs used in Acute MI will provide us specific knowledge regarding prescription in such patients
Aims and objectives
Study was conducted to study the pattern of prescription and to analyze various group of drugs and specific drugs used in Acute MI.
Material and methods
A prospective, non interventional, single centre, observational study was conducted on 100 acute MI patients admitted in ICCU at G.G Hospital, Jamnagar for the duration of one year and all the demographic details and medication records were noted in case record form for each patient.
Results
Out of 100 patients, 82% patients were males and maximum e.g.45% were of age > 60 years. The percentages of patients who received Antiplatelet Agents, Thrombolytics, Beta Blockers, ACE inhibitors, Calcium Channel Blockers, Antianginal Drugs, Hypolipidaemics, Opioids, and Antacids were 97%, 43%, 22%,78%, 15%, 55%, 84%, 73%, and 81% respectively. Prescription of drugs per encounter was 9.38% with dominance of generic prescription.
Conclusion
Present study provide us with precious insight regarding pattern of drug used in patients of acute MI. Rational drug use with Generic prescription is needed for effective treatment.
Keywords
Article Details
References
- [1]. Jones DS, Podolsky SH, Greene JA. The burden of disease and the changing task of medicine. N. Engl. J. Med. 366, 2012, 2333–2338.
- [2]. Enas EA, Senthikumar A. Coronary Artery Disease in Indians: The Internet journal of cardiology, 1, 2001.
- [3]. Schiele F, Meneveau N, Seronde MF, Caulfield F, Fouche R, Lassabe G, et al. Compliance with guidelines and 1-year mortality in patients with acute myocardial infarction: a prospective study. Eur Heart J 26, 2005, 873-880.
- [4]. Gislason GH, Rasmussen JN, Abildstrom SZ, Gadsboll N, Buch P, Friberg J, et al. Long-term compliance with beta-blockers, angiotensinconverting enzyme inhibitors and statins after acute myocardial infarction. Eur Heart J 27, 2006, 1153-1158.
- [5]. Laporte JR, Baksaas I, Lunde PKM. General background. In Dukes MNG (Edn) Drug utilization studies methods and uses, WHO regional publication. European Copenhagen WHO. 45, 1993.
- [6]. Greenland P, Reiss HR, Goldbourt U, Solomon B. Israeli SPRINT Investigators, In Hospital and 1-Year Mortality in 1,524 Women After Myocardial Infarction. Comparison with 4, 315 men.Circulation. 83, 1991, 484-491
- [7]. Motarreb AL, Khawlani AL, Asri AL, Qudaimi Al, Saleh AH, Wazeer AL, Pattern Of Acute Myocardial Infarction Management At Coronary Care Units In Sana’a, Yemen – A Pilot Study. Heart Views; 6(3), 2005, 93- 97
- [8]. Patel Ramesh, Jawaid Talha, Shukla Kumar Parjanya and Singh Pratap Mahendra. Evaluation of Drug Utilization Pattern in Patient of Myocardial Infarction & Prevalence of the MI by Comparison of Age, Sex, Diet, Smokers & Non-smokers, Alcoholic & Nonalcoholic. American Journal of Pharmacology and Pharmacotherapeutic: 2(1), 2015, 072-080
- [9]. Ouyang P, Michos ED, Karas RH.Hormone Replacement Therapy and the Cardiovascular System. Journal of the American College of Cardiology: 47, 2006, 1741–53.
- [10]. Avula Naveen, Dr. MR Sravani and J Naresh Venkat. Drug utilization patterns in acute coronary syndrome at a tertiary care teaching hospital: A retrospective, non interventional and observational study. The Pharma Innovation Journal 6(9), 2017, 538-542
- [11]. Kamath A, Shanbhag T, Shenoy S. A Descriptive Study of the Influence of Age and Gender on Drug Utilization in Acute Myocardial Infarction. Journal of Clinical and Diagnostic Research. 4, 2010, 2041-46.
- [12]. Sreedevi K, Rao VJ, Fareedullah MD, Vijayakumar S. A study on prescription pattern of statins in cardiovascular disease. Der Pharmacia Lettre, 3, 2011, 393-396.
References
[1]. Jones DS, Podolsky SH, Greene JA. The burden of disease and the changing task of medicine. N. Engl. J. Med. 366, 2012, 2333–2338.
[2]. Enas EA, Senthikumar A. Coronary Artery Disease in Indians: The Internet journal of cardiology, 1, 2001.
[3]. Schiele F, Meneveau N, Seronde MF, Caulfield F, Fouche R, Lassabe G, et al. Compliance with guidelines and 1-year mortality in patients with acute myocardial infarction: a prospective study. Eur Heart J 26, 2005, 873-880.
[4]. Gislason GH, Rasmussen JN, Abildstrom SZ, Gadsboll N, Buch P, Friberg J, et al. Long-term compliance with beta-blockers, angiotensinconverting enzyme inhibitors and statins after acute myocardial infarction. Eur Heart J 27, 2006, 1153-1158.
[5]. Laporte JR, Baksaas I, Lunde PKM. General background. In Dukes MNG (Edn) Drug utilization studies methods and uses, WHO regional publication. European Copenhagen WHO. 45, 1993.
[6]. Greenland P, Reiss HR, Goldbourt U, Solomon B. Israeli SPRINT Investigators, In Hospital and 1-Year Mortality in 1,524 Women After Myocardial Infarction. Comparison with 4, 315 men.Circulation. 83, 1991, 484-491
[7]. Motarreb AL, Khawlani AL, Asri AL, Qudaimi Al, Saleh AH, Wazeer AL, Pattern Of Acute Myocardial Infarction Management At Coronary Care Units In Sana’a, Yemen – A Pilot Study. Heart Views; 6(3), 2005, 93- 97
[8]. Patel Ramesh, Jawaid Talha, Shukla Kumar Parjanya and Singh Pratap Mahendra. Evaluation of Drug Utilization Pattern in Patient of Myocardial Infarction & Prevalence of the MI by Comparison of Age, Sex, Diet, Smokers & Non-smokers, Alcoholic & Nonalcoholic. American Journal of Pharmacology and Pharmacotherapeutic: 2(1), 2015, 072-080
[9]. Ouyang P, Michos ED, Karas RH.Hormone Replacement Therapy and the Cardiovascular System. Journal of the American College of Cardiology: 47, 2006, 1741–53.
[10]. Avula Naveen, Dr. MR Sravani and J Naresh Venkat. Drug utilization patterns in acute coronary syndrome at a tertiary care teaching hospital: A retrospective, non interventional and observational study. The Pharma Innovation Journal 6(9), 2017, 538-542
[11]. Kamath A, Shanbhag T, Shenoy S. A Descriptive Study of the Influence of Age and Gender on Drug Utilization in Acute Myocardial Infarction. Journal of Clinical and Diagnostic Research. 4, 2010, 2041-46.
[12]. Sreedevi K, Rao VJ, Fareedullah MD, Vijayakumar S. A study on prescription pattern of statins in cardiovascular disease. Der Pharmacia Lettre, 3, 2011, 393-396.