Main Article Content

Abstract

Middle East Respiratory Syndrome Coronavirus is the species of genus Beta Coronavirus. A novel human coronaviruses are single-stranded RNA. They are distinct from SARS and common cold viruses. First case of MERS-CoV was reported in Saudi Arabia in April 2012, in patients with severe Pneumonia. MERS-CoV has mild to non-specific symptoms which includes Headache, vomiting, High fever, cough, etc. MERS-CoV has been reported under high mortality rate. It is diagnosed through PCR (Polymerase Chain Reaction) and virus isolation from respiratory tracts and blood samples. No Antiviral agents or vaccines are available for this disease.

Keywords

Middle East Respiratory Syndrome Coronavirus MERS-CoV Sign and symptoms Diagnosis Precaution Treatment

Article Details

How to Cite
Mehta Shachi. (2021). A new looming of Middle East respiratory syndrome coronavirus MERS-CoV. International Journal of Research in Pharmacology & Pharmacotherapeutics, 5(4), 326-331. Retrieved from https://ijrpp.com/ijrpp/article/view/370

References

  1. [1]. World Health Organization (WHO). Coronavirus infections. Geneva: WHO. [Accessed 2016].
  2. [2]. Available from: http:// www.who.int/emergencies/mers-cov/saudi-arabia-update/en/
  3. [3]. Raoul J., Susan C., Ralph S., Caroline S., “Identification of a novel coronavirus as a cause of severe respiratory disease”, Journal of Virology, 87(14), 2013, 7790-7792.
  4. [4]. Zaki AM, Van Boheemen S, Bestebroer TM, “Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia”, the New England journal of medicine, 367(19), 2012, 1814-20.
  5. [5]. Annan A., Baldwin HJ, “Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe”, emerging infectious disease, 19(3), 2013, 456-9.
  6. [6]. Danielsson N, “Novel coronavirus associated with severe respiratory disease: case definition and public health measure”, Eurosurveillance, 17(39), 2012.
  7. [7]. Centers for Disease control and Prevention, “Information about Middle East Respiratory Syndrome” [Accessed on 2016]
  8. [8]. Available from: https://www.cdc.gov/coronavirus/mers/
  9. [9]. Dr Benoit G, Julien P, “Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission”, the lancet, 381(9885), 2013, 2265-2272.
  10. [10]. Ethiopian Public Health Institute, “Prevention and Control of Middle East Respiratory Syndrome Coronavirus (MERS-CoV)”, Interim guidelines, July 2014 [Accessed on 2016]
  11. [11]. Available from: http://www.ephi.gov.et/images/pictures/MERS-Coronavirus%20Guideline-Final16%202014.pdf
  12. [12]. Matthew C, Tommy T., Simon J., Anne L., “Full genome deep sequencing and phylogenetic analysis of novel human Betacoronavirus”, Emerging Infectious disease, 19(5), 2013.
  13. [13]. Brian R, Jessica R, Daniel F, David L., Mark A, “Update on the Epidemiology of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection, and Guidance for the Public, Clinicians, and Public Health Authorities — January 2015”, Morbidity and Mortality Weekly report, 64(03), 2015, 61-62.
  14. [14]. Zumla A, David S, Stanley P, “Middle East Respiratory Syndrome”, Lancet, 386(9997), 2015, 995-1007.
  15. [15]. Bushra H, Abdalla M, Arbash H, Alshayeb Z, “An outbreak of Middle East Respiratory Syndrome (MERS) due to coronavirus in Al-Ahssa Region, Saudi Arabia, 2015”, Eastern Mediterranean health Journal, 22(7), 2016, 468-475.
  16. [16]. Arabi M, Ahmed A, Hanan H, Hani N, “Clinical Course and Outcomes of Critically Ill Patients With Middle East Respiratory Syndrome Coronavirus Infection”, Annals of Internal medicines, 160(6), 2014.
  17. [17]. Basem A, Noha B, Haneen Q, Hanadi A, Abeer A, “Patient characteristics infected with Middle East respiratory syndrome coronavirus infection in a tertiary hospital”, Annals of Thoracic medicine, 11(2), 2016, 128-131.
  18. [18]. Mishra B, “Combating the spread of Middle East respiratory syndrome coronavirus: Indian perspective”, Indian journal of medical microbiology, 34(2), 2016, 135-136.
  19. [19]. Reusken CB, Haaqmans BL, Muller MA, Gutierrez C, “Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study”, Lancet Infectious disease, 13(10), 2013, 859-66.
  20. [20]. Petersen E, David S, Stanley P, “Middle East Respiratory Syndrome– advancing the public health and research agenda on MERS- lessons from the South Korea outbreak”, International journal of Infectious disease, 36, 2015, 54-55.
  21. [21]. Dyall J, Coleman CM, Hart BJ, Venkataram T, “Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection”, Antimicrobial agents and chemotherapy, 58(8), 2014, 4885-93.
  22. [22]. Chan J, Chan KH, Kao RY, To KK, “Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus”, The journal of Infections, 67(6), 2013, 606-10.