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May 9, 2021
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May 9, 2021
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Abstract

Introduction


Irrational use of medication is one of the main causes of resistance. It can be prevented by giving right drug to right patients. Hence the present study was conducted to evaluate the prescribing pattern and rational drug use in cases of enteric fever.


Aim


To study of prescription pattern and rational drug use in cases of enteric fever in a tertiary care hospital.


Methods


A cross sectional study was carried out by evaluating prescription of 161 subjects who had definite diagnosis of enteric fever in Department of Pharmacology in collaboration with Department of General Medicine at Government Medical College, Kannauj from May 2018 to July 2018. The data was analyzed by using SPSS software and results were expressed as percentage.


Results


In this study among 161 patients of enteric fever, 56.52% were males and 43.47% were females. There were two subset of age groups in which enteric fever is most common i.e. 58.3% in age group between 21 to 40 years followed by 27.9% in age group between 1 to 20 years. Most commonly prescribed antimicrobial agents were IIIrd generation Cephalosporin’s (70.1%) followed by 1st Generation Fluoroquinolones (51.5%). Some patients also received other groups of antibiotics like Macrolides (16.1%), Metronidazole (3.7%) and Penicillins (0.6%). All the medications were prescribed using their generic names and in small letters of English. They were prescribed oral medications (86.95%) and were duly signed by the physicians but none of them followed up. 93.1% received Paracetamol as antipyretic and 2.4% of the patients received Metaclopramide as antiemetic.


Conclusions


The present study provided prescribing pattern in outdoor patients of tertiary hospital which highlighted the current drawbacks like polytherapy, not abiding with antibiotic policy and principles of pharmacoeconomics in prescribing antibiotics to patients of enteric fever. There was less possibility of doing sensitivity test and prescribing them single drug therapy in tertiary care hospital because most of the critical patients are referred from other centres.

Keywords

Typhoid Prescription Pattern Rational use of drugs

Article Details

How to Cite
Dr. Virendra Kushwaha, Dr. Mohit Trivedi, Mr. Nagesh Chaganti, Dr. Pooja Agrawal, & Dr. Tanu Midda. (2021). Prescription pattern and rational drug use in cases of enteric fever in a tertiary care hospital. International Journal of Research in Pharmacology & Pharmacotherapeutics, 7(4), 299-303. https://doi.org/10.61096/ijrpp.v7.iss4.2018.299-303
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References

  1. [1]. Gupta AK, Basaj SS. Introduction to Pharmaceutics. Delhi, India:CBS Publisher and Distributors; 2(4), 2007.
  2. [2]. De Vries TP, Henning RH, Hogerzeil HV, Fresle DA. In: World Health Organization, editor. Guide to Good Prescribing: A Practical Manual. Geneva: World Health Organization (WHO/DAP/94.11); 1995, 52-55.
  3. [3]. Calligaris L, Panzera A, Arnoldo L, Londero C, Quattrin R, Troncon MG, et al. Errors and omissions in hospital prescriptions: A survey of prescription writing in a hospital. BMC ClinPharmacol 13, 2009, 9:9.
  4. [4]. Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D, et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. JAMA 274(1), 1995, 29-34.
  5. [5]. Crump JA, MintzLS. The global burden of typhoid fever. Bull World Health Organ 82, 2004, 346-53.
  6. [6]. Mahmud AK, Chowdhury AJ, Sarker ZM, Miah RA, Saleh AA, Mandal RM, et al. Typhoid fever. Mymensingh Med J 17(2), 2008, 236-44.
  7. [7]. Tamuno I, Fadare JO. Drug prescription pattern in a nigerian tertiary hospital. Trop J Pharm Res.11, 2012, 146-52.
  8. [8]. Gopal VD, Krishna RT, Kumar SA, Meda VS, Reddy RK. Prescribing pattern of antibiotics in the general medicine and pediatrics departments of a tertiary care teaching hospital. Int J Pharm Pharm Sci. 6, 2014, 221-4.
  9. [9]. Rani UM. Comparative study of efficacy of cefuroxime and ceftriaxone in enteric fever. IOSR J Dent Med Sci.14, 2015, 27-32.
  10. [10]. Rathod PS, Pravin S, Praveenkumar T. Patil, Balwant K. Choure, A. W. Patil. Study of current prescribing pattern of antimicrobial drugs in indoor cases of enteric fever in a tertiary care hospitalInt J Basic ClinPharmacol.5(1), 2016, 159-162
  11. [11]. Parikh FS. Management of enteric fever in 2012. Med Update.22, 2012, 12-4.
  12. [12]. Rahat SA, Muhammad AR, Hasan MM, Afroz F, Haque HF, Ahmed JU, Ahmed AS. Pattern of antibiotic sensitivity in enteric fever: a tertiary care hospital experience.J Med.15, 2014, 122-4.