Main Article Content
Abstract
Natural polymers derived from plants have gained significant attention in the field of wound healing due to their biocompatibility, biodegradability, and ability to promote tissue regeneration. These polymers, such as alginate, chitosan, and cellulose, possess unique properties that facilitate moisture retention, provide a protective barrier against infections, and enhance the healing process. The incorporation of natural plant extracts into these polymeric matrices further enhances their therapeutic potential by introducing bioactive compounds that can reduce inflammation and accelerate healing. This review explores the various types of natural plant-based polymers used in the formulation of wound-healing dressings and gels, highlighting their mechanisms of action, advantages over synthetic alternatives, and potential applications in modern medicine. The findings suggest that the integration of natural polymers in wound care not only improves healing outcomes but also aligns with the growing demand for sustainable and eco-friendly medical products.
Keywords
Natural Polymers
Wound Healing
Plant-derived
Biopolymers
Article Details
How to Cite
Natural Polymers from Plants are Used in Wound- Healing Dressings and Gels. (2025). International Journal of Research in Pharmacology & Pharmacotherapeutics, 14(3), 559-567. https://ijrpp.com/ijrpp/article/view/734
How to Cite
Natural Polymers from Plants are Used in Wound- Healing Dressings and Gels. (2025). International Journal of Research in Pharmacology & Pharmacotherapeutics, 14(3), 559-567. https://ijrpp.com/ijrpp/article/view/734
References
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References
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9.Mendes ISF, Prates A, Evtuguin DV. Production of rayon fibres from cellulosic pulps: State of the art and current developments. Carbohydrate Polymers. 2021 Dec;273:118466.
10.Firoozeh Danafar. RECENT DEVELOPMENT AND CHALLENGES IN SYNTHESIS OF CELLULOSIC NANOSTRUCTURES AND THEIR APPLICATION IN DEVELOPING PAPER-BASED ENERGY DEVICES. Cellulose Chemistry and Technology. 2020 Mar 4;54(3-4):327–46.
11.Oliveira C, Sousa D, Teixeira JA, Ferreira-Santos P, Botelho CM. Polymeric biomaterials for wound healing. Frontiers in Bioengineering and Biotechnology [Internet]. 2023 Jul 27;11:1136077. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415681/
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14.Shi S, Wang L, Song C, Yao L, Xiao J. Recent progresses of collagen dressings for chronic skin wound healing. Collagen and Leather. 2023 Oct 23;5(1).
15.Naomi R, Bahari H, Ridzuan PM, Othman F. Natural-Based Biomaterial for Skin Wound Healing (Gelatin vs. Collagen): Expert Review. Polymers. 2021 Jul 14;13(14):2319.
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17.Della Sala F, Longobardo G, Fabozzi A, di Gennaro M, Borzacchiello A. Hyaluronic Acid-Based Wound Dressing with Antimicrobial Properties for Wound Healing Application. Applied Sciences. 2022 Mar 17;12(6):3091.
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19.Kawano Y, Patrulea V, Sublet E, Borchard G, Iyoda T, Kageyama R, et al. Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure. Pharmaceuticals. 2021 Mar 28;14(4):301.
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2.Tavakoli M, Sheyda Labbaf, Marjan Mirhaj, Salehi S, Alexander Marcus Seifalian, Mahboubeh Firuzeh. Natural polymers in wound healing: From academic studies to commercial products. 2023 Apr 12;
3.Google Scholar [Internet]. Google.co.in. 2025 [cited 2025 Aug 25]. Available from: https://scholar.google.co.in/scholar?q=natural+polymers:+A+recent+review&hl=en&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&t=1756149359211&u=%23p%3D_tf_ZHb_Q4AJ
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8.Google Scholar [Internet]. Google.co.in. 2025 [cited 2025 Aug 25]. Available from: https://scholar.google.co.in/scholar?q=application+of+natural+polymers+in+wound+dressings&hl=en&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&t=1756150452949&u=%23p%3DX-H9vOhm6IwJ
9.Mendes ISF, Prates A, Evtuguin DV. Production of rayon fibres from cellulosic pulps: State of the art and current developments. Carbohydrate Polymers. 2021 Dec;273:118466.
10.Firoozeh Danafar. RECENT DEVELOPMENT AND CHALLENGES IN SYNTHESIS OF CELLULOSIC NANOSTRUCTURES AND THEIR APPLICATION IN DEVELOPING PAPER-BASED ENERGY DEVICES. Cellulose Chemistry and Technology. 2020 Mar 4;54(3-4):327–46.
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12.Gupta A, Sharma N, Khinchi MP, Agrawal D. A REVIEW ON NATURAL POLYMER. Asian Journal of Pharmaceutical Research and Development [Internet]. 2017 [cited 2025 Aug 25];134–45. Available from: https://www.ajprd.com/index.php/journal/article/view/89
13.Dodi G, Sabau RE, Crețu BEB ., Gardikiotis I. Exploring the Antioxidant Potential of Gellan and Guar Gums in Wound Healing. Pharmaceutics [Internet]. 2023 Aug 1;15(8):2152. Available from: https://www.mdpi.com/1999-4923/15/8/2152
14.Shi S, Wang L, Song C, Yao L, Xiao J. Recent progresses of collagen dressings for chronic skin wound healing. Collagen and Leather. 2023 Oct 23;5(1).
15.Naomi R, Bahari H, Ridzuan PM, Othman F. Natural-Based Biomaterial for Skin Wound Healing (Gelatin vs. Collagen): Expert Review. Polymers. 2021 Jul 14;13(14):2319.
16.Antoszewska M, Sokolewicz EM, Barańska-Rybak W. Wide Use of Hyaluronic Acid in the Process of Wound Healing—A Rapid Review. Scientia Pharmaceutica [Internet]. 2024 Jun 1;92(2):23. Available from: https://www.mdpi.com/2218-0532/92/2/23
17.Della Sala F, Longobardo G, Fabozzi A, di Gennaro M, Borzacchiello A. Hyaluronic Acid-Based Wound Dressing with Antimicrobial Properties for Wound Healing Application. Applied Sciences. 2022 Mar 17;12(6):3091.
18.Google Scholar [Internet]. Google.co.in. 2025 [cited 2025 Aug 25]. Available from: https://scholar.google.co.in/scholar?q=Beneficial+Effects+of+Hyaluronic+Acid&hl=en&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&t=1756152472646&u=%23p%3DY-U0RE0OQZYJ
19.Kawano Y, Patrulea V, Sublet E, Borchard G, Iyoda T, Kageyama R, et al. Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure. Pharmaceuticals. 2021 Mar 28;14(4):301.
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21.Tudoroiu EE, Dinu-Pîrvu CE, Albu Kaya MG, Popa L, Anuța V, Prisada RM, et al. An Overview of Cellulose Derivatives-Based Dressings for Wound-Healing Management. Pharmaceuticals. 2021 Nov 24;14(12):1215.
22.Lee CS, Hee Sook Hwang. Starch-Based Hydrogels as a Drug Delivery System in Biomedical Applications. Gels. 2023 Dec 4;9(12):951–1.