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Jul 26, 2025
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Jul 26, 2025
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Abstract

This research aimed to enhance the topical delivery of Tectona grandis through emulgel formulation. An aqueous extract from Tectona grandis leaves was prepared, serving as the active pharmaceutical ingredient, contributing wound healing properties. Emulgel formulations were developed using Carbopol 934 and 940 as gelling agents. The study investigated how the type of gelling agent, oil phase concentration, and emulsifying agent influenced drug release, utilizing various evaluation techniques. The goal was to design, formulate, and assess a gellified emulsion (Emulgel) incorporating high molecular weight water-soluble polymers. The prepared emulgels exhibited desirable physical properties, including color, homogeneity, consistency, spreadability, and pH stability. Carbopol 940 demonstrated superior drug release and favorable physical characteristics. Among the formulations, F6 showed optimal clarity, appearance, and viscosity (2250 cps). Stability studies confirmed that physical and rheological properties remained unchanged over two months. Ultimately, F6 with 3% w/w Carbopol 940 emerged as the most promising formulation, offering enhanced physicochemical properties. The wound healing potential of Tectona grandis is attributed to 1,4-Naphthoquinones, which effectively aid in treating scald and burn wounds. This study highlights the potential of emulgels in delivering therapeutic agents for improved wound care.   

Keywords

Tectona grandis Emulgel formulation Topical drug delivery Carbopol 940 Wound healing 1,4-Naphthoquinones

Article Details

How to Cite
Surisetty Sridevi, Goli Harshitha, Gaddampally Vaishnavi, Gannamaneni Shrutheesha, Goddumari Mahesh, & Gadipa Rajesh. (2025). Formulation and Evaluation of Tectona Grandis (Teak) Emulgel. International Journal of Research in Pharmacology & Pharmacotherapeutics, 14(3), 438-451. Retrieved from https://ijrpp.com/ijrpp/article/view/719
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