Main Article Content

Abstract

A novel poly herbal skin serum was formulated for depigmentation, using Psoralea corylifolia (Bakuchi) seed extract as the key active ingredient. The serum base included green tea extract, glycerine, niacinamide, Tween 20, sodium benzoate, and lavender oil. Three batches (F1, F2, F3) with 15%, 12%, and 10% Bakuchi extract respectively were prepared and evaluated. All batches were stable and non-irritating over 30days. The 15% Bakuchi formulation (F1) showed the highest efficacy in reducing dark spors and improving skin moisture in volunteer tests. These results suggest that the Bakuchi-containing serum can safely ligten hypo pigmented skin areas while providing hydration, offering a natural alternative to conventional chemical depigmenting agents.

Keywords

Psoralea corlifolia, skin pigmentation, herbal serum, tyrosinase inhibition, antioxidants, depigmentation.

Article Details

How to Cite
Sumithra.G, Dhinesh.T, Ponmadasamy.M, Savitha.D, Dhanalakshmi.K, Ajith Kumar.V, & L.V.Vigneshwaran. (2025). Formulation and Evaluation of Polyherbal Pigmentation Skin Serum . International Journal of Research in Pharmacology & Pharmacotherapeutics, 14(3), 297-302. https://doi.org/10.61096/ijrpp.v14.iss3.2025.297-302

References

  1. 1. Aglawe et al., Preparation and evaluation of poly herbal facial scrub. Journal of drug delivery and therapeutics, 2019; 9(2):61-63.
  2. 2. Gabriella Baki and Kenneth‟s Alexander. Introduction to cosmetic formulation and technology in 2015
  3. 3. Mr. Vishal Ashok Chaudhari, Dr. Manoj V. Girase, Mr. Bhushan Gulab Borase, Mr. Shashikant Kailas Bhoi, Miss. Kalyani Ashok Chaudhar."Formulation and evaluation of multipurpose herbal scrub in gel form using Limonia acidissima", IJRAR - International Journal of Research and Analytical Reviews (IJRAR), 2020; 7(2):637-649
  4. 4. J.B. wilkinsome and R.J. Moore, Harry Cosmetology, Longman Singapore, Publication Edition VII Page, 3,8,265,410-62-64.
  5. 5. Shlomo Nagdassi, Ekta, Toultou, Novel Cosmetic Delivery System Page No. 72.
  6. 6. Takeo mitsui, New Cosmetic Science, Page 45,321.
  7. 7. Cosmetology – Theory and practical Research Test Method analysis formulas Vol.II,Ed. Karlheinz Scharader and Andreas, Domsch.Sagrine text book of cosmetic tech., Vol.2, page No.27
  8. 8. Cotelle, N., Bernier, J.L., Henichart, J.P., Catteau, J.P., Gaydou, E. and Wallet, J.C.: Free Rad.Biol. Med., 13: 211-219 (1992).
  9. 9. Radi, R., Beckman, J.S., Bush, K.M. and Freeman, B.A.: Arc. Biochem. Biophys. 288: 481-487. (1991).
  10. 10. Nishikimi, M., Rao, N.A. and Yagi, K.: Biochem. Biophy. Res. Comm. 46: 849-864 (1972).
  11. 11. Nawar, W. W.: Lipids (O.R. Fennema ed.) Food Chem. New York: Marcel Dekker Inc. 3rd ed.,pp. 225-319 (1996).
  12. 12. Pietta, P.G.: J. Natural Products, 63: 1035-1042 (2000).
  13. 13. Yu, L., Haley, S., Perret, J., Harris, M., Wilson, J. and Qian, M. J.: Agric. Food Chem., 50: 1619-1624 (2002).