Main Article Content
Abstract
Background: Drug utilization research focuses on how drugs are marketed, prescribed, and used, along with their medical, social, and economic impact. WHO-developed indicators help assess and improve prescribing practices.
Aims & Objectives: 1) To evaluate drug utilization patterns in the Ophthalmology OPD of a tertiary care hospital. 2) To assess the rationality of prescriptions based on the National Essential Drug List (NEDL).
Methods: A prospective study was conducted in the Ophthalmology OPD of Sapthagiri Institute, Bangalore, from June to December 2022. A total of 1324 prescriptions were analyzed.
Results: Monotherapy was used in 63.8% of cases. Generic prescribing was high (99%). Most drugs were eyedrops (94.7%), followed by ointments and oral forms. Dosage and treatment duration were noted in nearly all prescriptions. Moxifloxacin was the most common antibiotic (27%). Antiallergics (158), NSAIDs (64), steroids (20), and anti-glaucoma drugs (25) were also prescribed. Prescription errors were minimal.
Conclusion: Prescribing was largely rational, aligned with NEDL, with low rates of polypharmacy and errors.
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Article Details
References
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- 4. Yasmeen Maniyar, Prabhu Bhixavatimath And Vidyashree Akkone. A Drug Utilization Study InThe Ophthalmology Department Of a Medical College, Karnataka, India Journal of Clinical and Diagnostic Research. 2011 Feb, Vol-5(1):82-84
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- 9. Jain VK, Shrivastava B, Agarwal M. Drug utilization pattern of drugs used along ophthalmic antiallergics formulations used in patients diagnosed with seasonal and perennial allergic conjunctivitis. Asian J Pharm Sci Res 2011;1:15-20.
- 10. Biswas NR, Jindal S, Siddiquei MM, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin Pharmacol 2001;51(3):267-9.
- 11. Maniyar Y, Bhixavatimath P, Akkone V. A drug utilization study in the ophthalmology department of a Medical College, Karnataka, India. J Clin Diagn Res 2011;5:82-4.
- 12. Banjara SK, Mudavath K, Bhukya KD. Pattern of prescription and drug use in ophthalmology out-patient department in a teaching hospital. Glob J Res Anal 2014;3:92-3.
- 13. Hasmnis AA, Patil SS, Narayan KA, Rashid AK, Mohanty BK. Drug utilization study for acute illnesses in village Banggol, Malaysia; the findings of a household survey. Al Ameen J Med Sci 2010;3:165-8.
- 14. Lee D, Bergman U. Studies of drug utilization. In: Storm BL, editors. Pharmacoepidemiology. Chichester, UK: John Wiley & Sons; 2005. p. 401-17.
- 15. Jadhav PR, Moghe VV, Deshmukh YA. Drug utilization study in ophthalmology outpatients at a tertiary care teaching hospital. ISRN Pharmacol 2013;2013:768792.
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- 18. Sharma D, Reeta K, Badyal DK, Garg SK, Bhargava VK. Antimicrobial prescribing pattern in an Indian tertiary hospital. Indian J Physiol Pharmacol 1998;42(4):533-7.
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- 22. Mirza NY, Desai S, Ganguly B. Prescribing pattern in a pediatric out-patient department in Gujarat.Bangladesh Journal of Pharmacology. 2009;4(1):39–42.
- 23. Duggirala A, Joseph J, Sharma S, Nutheti R, Garg P, Das T. Activity of newer fluoroquinolones against gram-positive and gram-negative bacteria isolated from ocular infections: an in vitro comparison. Indian Journal of Ophthalmology. 2007;55(1):15–19.
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- 25. Biswas NR, Jindal S, MairajSiddiquei M, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. British Journal of Clinical Pharmacology. 2001;51(3):267–269.
- 26. Maniyar Y, Bhixavatimath P, Akkone V. A drug utilization study in the ophthalmology department of a medical college, Karnataka, India. Journal of Clinical and Diagnostic Research. 2011;5(1):82–84.
- 27. Mohanty M, Mohapatra S. Drug utiliation pattern of topical ocular antimicrobials in a tertiary care hospital. Indian Journal of Pharmacology. 2003;35(6):p. 399.
- 28. Pradhan SC, Shewade DG, Tekur U, et al. Changing pattern of antimicrobial utilization in an Indian teaching hospital. Int J ClinPharmacolTherToxicol. 1990;28:339–343
- 29. Nehru M, Kohli K, Kapoor B, Sadhotra P, Chopra V, Sharma R. Drug utilization study in outpatient ophthalmology department of Government Medical College. JK Science.2005;7:149–51.
- 30. World Health Organization. How to investigate drug use in health facilities. Selected drug use indicators. WHO/DAP/93.1. WHO, Geneva, 1993
References
1. Pooja prajwal, Mohandas Rai, Sharat kumar, Shrinivas Bhat U, Floyd Vernon D Souza, Drug utilisation pattern in ophthalmology Dept at a tertiary care hospital, Pooja Prajwal et al, Int J Pharm.2013,4(8)
2. Hardik V Vaniya, Nishita H Darji, Vikas R Patel, Devdatta J Gohel, Drug Utilization Study in Ophthalmology Outpatients in a Tertiary Care Hospital Advances in Pharmacology and Pharmacy 4(2): 11-15, 2016
3. Bhavesh k. lalan, R. S. Hiray, B. B. Ghongane “Drug prescription pattern of outpatients in a tertiary care teaching hospital in maharashtra” Int J Pharm Bio Sci 2012 July; 3(3): P 225 - 229
4. Yasmeen Maniyar, Prabhu Bhixavatimath And Vidyashree Akkone. A Drug Utilization Study InThe Ophthalmology Department Of a Medical College, Karnataka, India Journal of Clinical and Diagnostic Research. 2011 Feb, Vol-5(1):82-84
5. Amit kumar jain, seema jain, vikrant sharma, dadan ji pandey, anand Shukla, Drug utilization study in ophthalmology outpatient department in a tertiary care teaching hospital of western uttar pradesh, india” Asian J Pharm Clin Res, Vol 9, Issue 1, 2016, 354-356
6. Gangwar A, Singh R, Singh S, Sharma BD. Pharmacoepidemiology of drugs utilized in ophthalmic outpatient and inpatient department of a tertiary care hospital. J Appl Pharm Sci 2011;1;135-40
7. The Pursuit of Responsible use of Medicines: Sharing and Learning from Country Experiences. Available from: http://www.apps.who.int/ iris/bitstream/10665/75828/1/WHO_EMP_MAR_2012.3_eng. pdf
8. Nehru M, Kohli K, Kapoor B, Sadhotra P, Chopra V, Sharma R. Drug utilization study in out-patient ophthalmology department of Government Medical College Jammu. JK Sci 2005;7(3):149-51.
9. Jain VK, Shrivastava B, Agarwal M. Drug utilization pattern of drugs used along ophthalmic antiallergics formulations used in patients diagnosed with seasonal and perennial allergic conjunctivitis. Asian J Pharm Sci Res 2011;1:15-20.
10. Biswas NR, Jindal S, Siddiquei MM, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin Pharmacol 2001;51(3):267-9.
11. Maniyar Y, Bhixavatimath P, Akkone V. A drug utilization study in the ophthalmology department of a Medical College, Karnataka, India. J Clin Diagn Res 2011;5:82-4.
12. Banjara SK, Mudavath K, Bhukya KD. Pattern of prescription and drug use in ophthalmology out-patient department in a teaching hospital. Glob J Res Anal 2014;3:92-3.
13. Hasmnis AA, Patil SS, Narayan KA, Rashid AK, Mohanty BK. Drug utilization study for acute illnesses in village Banggol, Malaysia; the findings of a household survey. Al Ameen J Med Sci 2010;3:165-8.
14. Lee D, Bergman U. Studies of drug utilization. In: Storm BL, editors. Pharmacoepidemiology. Chichester, UK: John Wiley & Sons; 2005. p. 401-17.
15. Jadhav PR, Moghe VV, Deshmukh YA. Drug utilization study in ophthalmology outpatients at a tertiary care teaching hospital. ISRN Pharmacol 2013;2013:768792.
16. Krishnaswamy K, Kumar BD, Radhaiah G. A drug survey – precepts and practices. Eur J Clin Pharmacol 1985;29(3):363-70. 20. Rambhade S, Chakarborty A, Shrivastava A, Patil UK, Rambhade A. A survey on polypharmacy and use of inappropriate medications. Toxicol Int 2012;19(1):68-73.
17. Nolan L, O’Malley K. Prescribing for the elderly. PartI: Sensitivity of the elderly to adverse drug reactions. J Am Geriatr Soc 1988;36(2):142-9.
18. Sharma D, Reeta K, Badyal DK, Garg SK, Bhargava VK. Antimicrobial prescribing pattern in an Indian tertiary hospital. Indian J Physiol Pharmacol 1998;42(4):533-7.
19. Gangwar A, Singh R, Singh S, Sharma BD. Pharmacoepidemiology of drugs utilized in ophthalmic outpatient and inpatient department of a tertiary care hospital. J Appl Pharm Sci 2011;1;135-40
20. World Health Organization (WHO) International Working Group for Drug Statistics Methodology, WHO Collaborating Centre for Drug Statistics Methodology, WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services. Introduction to Drug Utilization Research. Oslo, Norway: WHO; 2003.
21. Lee D, Bergman U. Studies of drug utilization. In: Storm LB, editor. Pharmacoepidemiology. Chichester, UK: John Wiley & Sons; 2005. pp. 401–417.
22. Mirza NY, Desai S, Ganguly B. Prescribing pattern in a pediatric out-patient department in Gujarat.Bangladesh Journal of Pharmacology. 2009;4(1):39–42.
23. Duggirala A, Joseph J, Sharma S, Nutheti R, Garg P, Das T. Activity of newer fluoroquinolones against gram-positive and gram-negative bacteria isolated from ocular infections: an in vitro comparison. Indian Journal of Ophthalmology. 2007;55(1):15–19.
24. Afshari NA, Ma JJK, Duncan SM, et al. Trends in resistance to ciprofloxacin, cefazolin, and gentamicin in the treatment of bacterial keratitis. Journal of Ocular Pharmacology and Therapeutics. 2008;24(2):217–223
25. Biswas NR, Jindal S, MairajSiddiquei M, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. British Journal of Clinical Pharmacology. 2001;51(3):267–269.
26. Maniyar Y, Bhixavatimath P, Akkone V. A drug utilization study in the ophthalmology department of a medical college, Karnataka, India. Journal of Clinical and Diagnostic Research. 2011;5(1):82–84.
27. Mohanty M, Mohapatra S. Drug utiliation pattern of topical ocular antimicrobials in a tertiary care hospital. Indian Journal of Pharmacology. 2003;35(6):p. 399.
28. Pradhan SC, Shewade DG, Tekur U, et al. Changing pattern of antimicrobial utilization in an Indian teaching hospital. Int J ClinPharmacolTherToxicol. 1990;28:339–343
29. Nehru M, Kohli K, Kapoor B, Sadhotra P, Chopra V, Sharma R. Drug utilization study in outpatient ophthalmology department of Government Medical College. JK Science.2005;7:149–51.
30. World Health Organization. How to investigate drug use in health facilities. Selected drug use indicators. WHO/DAP/93.1. WHO, Geneva, 1993