Main Article Content
Abstract
Background: Cancer is a life-threatening disease that causes death. Cancer is the leading cause of death. There are several factors for the formation of cancers. According to survey conducted by the International Agency for Research on Cancer (IARC) and the American Cancer Society (ACS) in 2022 20 million new cancer cases are raised by 2022 and 9.7 million deaths.
Aim/Objectives: This study assesses the prescription patterns and therapeutic approaches for various types of cancer. To evaluate the drug prescription patterns of Anti-Cancer drugs in cancer patients in tertiary care hospital, to observe different dose regimens, to study the efficacy of anti-cancer drugs in various cancer chemotherapies, and to determine the survival rate in cancer patients.
Materials &methods: A retrospective observational study in a period of 5 months in a tertiary care hospital.
Results: A total of 80 patients are enrolled in this study after diagnosed as the cancer. And majority of cancer patients are females. And cancer attacks majorly in the age group of 51-60. Cervix, and breast cancers in females are more. Based on the condition and severity of the patients the different types of cytotoxic drugs are used. Majorly the platinum-based drugs like cisplatin, carboplatin, and oxaliplatin are used. The drugs like ondansetron, dexamethasone, chlorpheniramine maleate, ranitidine, pantoprazole, and etc,. drugs are given to control or to suppress, the side effects caused by the cytotoxic drugs.
Conclusion: The cytotoxic drugs are given in a controlled manner, there is a gap of 3 weeks for every chemotherapy cycle. The quality of life and survival rate can be increased by chemotherapy but there is a chance of death.
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References
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References
1. Freddle Bray, Mathleu Laversanne, Hyuna Sung, Jacques Ferlay, Rebecca L, et al., Global cancer statistics 2022: GLOBOCAN estimate of incidence and mortality worldwide for 36 cancers in 185 countries. A cancer journal of clinicians. 04 April 2024 volume 74, issue 3 p. 229-263.
2. Camilla Mattiuzzi, Giuseppe Lippi. Current cancer epidemiology. National library of medicine. 2019 Dec;9(4):p 217-222.
3. Dr. Ananya Mandal, MD. Cancer pathophysiology. News medical life sciences. April 24, 2019.
4. Shuel SL. Targeted cancer therapies: Clinical pearls for primary care. Can Fam Physician. 2022 Jul;68(7):515-518. doi: 10.46747/cfp.6807515. PMID: 35831091; PMCID: PMC9842142.
5. Ramya teja Medarametla, Gadela Venkata Radha. QbD Based development, characterization and pharmacokinetic evaluation of Enzalutamide-loaded Cyclodextrin Nano Sponges for Enhanced drug delivery. Indian journal of pharmaceutical education and research. Volume 59, issue 1s 2025, p s89-s101.
6. M. Ramya Teja, G.V. Radha. Recent Progress in Nanosponge Technology: Opportunities and Challenges in Cancer Treatment. Scope, 2023;13(4):826-837.
7. Jain, Shipra; Upadhyaya, Prerna; Goyal, Jaswant; Kumar, Abhijit; Jain, Pushpawati; Seth, Vikas1; Moghe, Vijay V2. A systematic review of prescription pattern monitoring studies and their effectiveness in promoting rational use of medicines. Perspectives in Clinical Research 6(2): p 86-90, Apr–Jun 2015. Doi: 10.4103/2229-3485.154005.
8. Wang H, Li N, Zhu H, Xu S, Lu H, Feng Z (2013) Prescription Pattern and Its Influencing Factors in Chinese County Hospitals: A Retrospective Cross-Sectional Study. PLoS ONE 8(5): e63225.
9. Nori Kodanda ram, P. Akshay, K. Triveni, Sk. Shameera, J. Tharun naik, T. Gopinath, J. N. Suresh Kumar. A review on tumor markers (CEA, CA-19.9, and CA242) as a powerful diagnostic and therapeutic tools in colorectal cancer. International journal of pharmacology and clinical research. 8(3); p356-361, 2024.
10. Anna N. Wilkinson. Cancer diagnosis in primary care. Oncology briefs. Vol 67, 2021, p 265-268.
11. Chemotherapy to treat cancer, National cancer institute, August 23, 2022
12. KD Tripathi. Essentials of MEDICINAL PHARMACOLOGY. 6th edition.2006
13. Nori Kodanda ram, Shameera. Sk, Akshay. P, Triveni. K, Gopinath. T, Tharun naik. J.N.S. Kumar. A review on colorectal cancer and its chemotherapeutic management. International journal of pharmacology and clinical research. Vol-8, issue-3, p350-355, 2024.
14. Nori Kodanda ram, K. Triveni, P. Akshay, Sk. Shameera, J. Tharun naik, T, Gopinath, J.N. Suresh Kumar. A review on role of oncogene (KRAS) & tumor suppressor gene (TP53) in colorectal cancer. Vol-12, iss-4, p596-599.