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Abstract

During the epidemic season, over 90% of respiratory disease is associated with bronchial Asthma. Both Allergens and Inflammatory mediators mediated inflammation have been involved in the pathophysiology of Asthma, but oxidative stress in respiratory cells has been shown to be dominant. The on-going inflammation increases the chemotaxis of oxidative stress to inflamed site providing to their production. The pharmacological production of oxidative stress can be suppressed with Natural Antioxidants. Screening of traditional plants which can be used in treatment of respiratory tracts disorders (e.g. Asthma), we have selected some herbs or plants which can be a potential source of antioxidant compounds for limiting of oxidative stress in Asthma. The books on ethno-medicine, pharmacology and pharmacognosy includingEthnomedicine book by Pamela Erickson, Goodman and Gilman's The Pharmacological Basis of Therapeutics, by Goodman, L. S., Gilman, A., Hardman, J. G., Gilman, A. G., &Limbird, L. E., Trease and Evans Pharmacognosy Textbook by William Charles Evans and etc were explored for Asthma, Antioxidants,Allium sativum,Artemisia annua,Anchomanesdifformis, Saururuschinensis, Mentha, Petasites japonicas, Phytolaccaesculentaand other traditional plants. Additionally, information on the ethno-botany, Phytochemistry, morphology, taxonomy, modern medicinal uses, and pharmacological activities were collected in electronic databases including Google Scholar, Science Direct, Scopus, and PubMed using the keywords "Asthma," "traditional medicine for Asthma," "ethnomedicine," "Natural Antioxidants," "pathogenesis of asthma" and "Oxidative stress in asthma." Then, the available articles from 1975 to 2020 were employed for this study.Alliumsativum,Artemisia annua,Anchomanesdifformis, Saururuschinensis, Mentha, Petasites japonicas, Phytolaccaesculentaand some other traditional herbs or plants have shown a potential antioxidant activity for the suppression of oxidative stress. These herbs were used traditionally in formularies or by rural people as Anti-cough, Anti-allergic and etc. In modern medicine, the extract of these natural herbs showed antioxidant activity. Asthma is a chronic airway disease which cannot be cured permanently with anti-asthmatic drugs. Anti-asthmatic drugs have various side effects on the vital organs of the body. Thus, there is necessary to treat the asthma with some natural herbs. The below mentioned Natural herbs having the potential antioxidant activity which exhibits important role in the treatment of the Asthma.

Keywords

Asthma Natural Antioxidants Oxidative Stress Inhibitors Antioxidant treatment of asthma

Article Details

How to Cite
Chandan Chauhan, Shantanu Singh, Anshita, Sachin Kumar, & Sanjiv Singh. (2021). Natural Antioxidants: Potential Oxidative Stress Inhibitors for the Treatment of Asthma. International Journal of Research in Pharmacology & Pharmacotherapeutics, 10(1), 48-57. Retrieved from https://ijrpp.com/ijrpp/article/view/62

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