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Jul 4, 2024
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Jul 4, 2024
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Abstract

Natural compounds can be a lead compounds, allowing the design and rational planning of new drugs, biomimetic synthesis development and the discovery of new therapeutic properties not yet attributed to known compounds. The present study has made an attempt to evaluate the Phytochemical screening and antifungal activity of Neolamarckia cadamba Roxb.  leaf extract (NCLE). Antifungal activity of Neolamarckia cadamba was conducted on fungal organism on Aspergillus niger. From phytochemical screening of the crude aqueous, ethanolic & cyclohexane extract of the leaves of showed the presence of Alkaloids, Tannins, Saponins, Steroids and Glycosides. In biological evaluation, the antifungal activities of aqueous, ethanolic & cyclohexane extract of Neolamarckia cadamba under the varying concentration of 25, 50, 75, 100 μg/ml tested against Aspergillus niger. Zone of inhibition of aqueous, ethanolic & cyclohexane extracts were compared with that of standards like Flucanazole in which the aqueous extract of NCLE showed a better antifungal activity next to the standard.  The aim of the current research investigation was to perform the extraction, preliminary phytochemical screening and to evaluate the invitro antifungal activity of fruit of Neolamarckia cadamba.

Keywords

Neolamarckia cadamba antifungal activity agar plate method phytochemicals

Article Details

How to Cite
V.A.N.V. Haritha, Alapati Geethika, Rakam Gopi Krishna, Boddu Harika, Goppa Saraswathi, & Gayakwad Rajeshwar. (2024). Phytochemical Screening & Comparative study of different extracts on Antifungal Activity of Neolamarckia cadamba leaf. International Journal of Research in Pharmacology & Pharmacotherapeutics, 13(3), 254-264. Retrieved from https://ijrpp.com/ijrpp/article/view/553
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