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Over the past decades, research on the pathophysiology of cardiac dysfunction has increasingly focused on inflammation. The mediators of inflammation and indicators have become crucial for better understanding and diagnosing atherosclerotic heart disease (AHD) and congestive heart failure at the early stages of pathophysiology. CVDs include CAD (coronary artery disease) and atherosclerosis and many inflammation-mediated cardiac dysfunction, CHF, and cardiac reperfusion damage. The cytokines known as pro-inflammatory interleukin/IL-1, 6, 8, 11, 16, 17, tumour necrosis factors, granulocyte colony-stimulating factors. The cytokines that are either directly or indirectly responsible for cardiovascular disorders, coordinate responses to inflammatory factors. In this review, we have discussed the latest research on the topic as well as the cytokines and chemokines that are linked to CVD.


Cardiovascular disease (CVD), Cardiomyopathy, Cytokines, Heart failure, Inflammation.

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How to Cite
Binaya Kumar Sethy, Mrinmoy Kumar Ghosh, & Sandipan Dash. (2024). Role of Inflammatory Cytokines and Chemokines in the Pathological Progression of Cardiovascular Disease (CVD): A Detailed Review. International Journal of Research in Pharmacology & Pharmacotherapeutics, 13(1), 31-42.


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