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Peptic ulcer disease is a serious gastrointestinal disorder that requires well targeted therapeutic strategy. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but clinical evaluation of these drugs has shown incidence of relapse, side effects and drug interactions. This has been rational for the development of new anti ulcer drugs and search for novel molecules has been extended to herbal that offer better protection and relapse. The present study is to evaluate the anti ulcer activity by using herbal remedy Psydrax dicoccum. The methanolic extract of Psydrax dicoccum treated groups shows a significant effect when compared to control group animals which indicating that the plant having the anti ulcer activity. And also the results showed - that the methanolic extract of the Psydrax dicoccum having the antioxidant activity. The acute toxicity study conducted for methanolic extract of Psydrax dicoccum indicates that safe up to 2000mg/kg body weight. Ulcer can minimize by some life style changes like, avoid alcohol, caffeine beverages (coffee and pop), fatty foods, and highly seasoned foods. Also try to minimize stress in life.  Stress may worsen ulcer symptoms.


Psydrax dicoccum, Anti Ulcer, Methanolic

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How to Cite
T.Prathyusha, Shaik Abdul khaliq, Sharifunnisa nikhat, S.Prashanth, & R. Hemalatha. (2022). Evaluation of anti-ulcer activity of methanolic extract of psydrax dicoccos in experimental rats. International Journal of Research in Pharmacology & Pharmacotherapeutics, 11(2), 103-109. Retrieved from


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