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Abstract

Adenanthera pavonina L(mimosidae) is a deciduous tree, also known as red sandal wood or coral wood tree. The leaves and bark of this plant are used by Irula tribals for curing various ailments like diarrhoea, asthma, jaundice, tuberculosis, leprosy, rheumatism, hypertension, wound healing, diabetes, inflammation, and cancer. Leaves posseses anti-inflammatory, anti- arthritic, antioxidant, antinociceptive, antiemetic, hypoglycemic, antibacterial, cytotoxicity, radical scavenging activity. Phytochemical review showed the presence of carbohydrates, proteins, flavonoids, phenols, sterols, saponins, glycosides, tannins, alkaloids. The literature review revealed the pharamacognostical preliminary phytochemical evaluation was not investigated. An endeavor study was taken to investigate pharmacognostical, preliminary phytochemical screening, quantitative estimation and invitro anti-oxidant activity. Transverse section of petiole, rachis, midrib, the stomata are strictly paracytic type, thick walled uniserate, simple trichomes are present. Powder microscopy of leaf showed presence of thick walled simple trichomes, reticulate vessels, prismatic crystals and scelreids. The quantitative microscopical parameters such as stomatal number (100-128/mm2), stomatal index (11-13/mm2), vein islet number (2-3/mm2) and vein termination number(51-64/mm2), palisade ratio(3-5/mm2). Physicochemical parameters such as loss on drying (6.61±0.39%w/w), total ash(15.83± 0.05%w/w), ethanol extractive value(26.30±0.57),aqueous extractive value(36.73±2.05). Preliminary phytochemical screening of this plant revealed the presence of carbohydrates, proteins, tannins, flavonoid, steroids, saponins, phenols. Quantitative estimation of gallic acid (35gm/gm), tannic acid (86gm/gm) & rutin (252mg/gm) were determined and correlated with standard. In-vitro anti-oxidant by hydrogen peroxide (16.32 µg/mL), nitric oxide (5.58 µg/mL), total antioxidant(24.67 µg/mL) & method were estimated and in comparison with ascorbic acid used as standard.

Keywords

Adenanthera pavonina phytochemical quantitative estimation antioxidant

Article Details

How to Cite
A. Krishnaveni, P. G. S. Danyalakshmi, D. Kothai Andal, T. Venkata Rathina Kumar, & A. Abdul Hasan Sathali. (2022). Pharmacognostical, preliminary phytochemical screening, estimation of phyto constituents and its in-vitro antioxidant activity of Adenanthera pavonina linn (leaves). International Journal of Research in Pharmacology & Pharmacotherapeutics, 11(2), 62-75. https://doi.org/10.61096/ijrpp.v11.iss2.2022.62-75

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