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Abstract

Desmodium triflorum, which is commonly known as “three-flowered beggar weed” is a dicotyledon, family Fabaceae. The present study was carried out to evaluate the immunomodulatory activity of aqueous extract of D. triflorum on Swiss albino rats. Delayed type hypersensitivity response and Humoral antibody titer by using injecting 0.1 ml of Sheep red blood cells (SRBCs) suspension was used to assess the activity of drug. Levamisole was given in the dose of 50 mg/kg body weight through oral route. 200 and 400 mg/kg body weight of Desmodium triflorum herbal drug was given through oral route. The extent of protection against SRBCs suspension was evaluated with drug administration by estimating total leucocyte and differential leucocyte count. aqeuous extract of D. triflorum showed pronounced immunostimulant activity by increasing the levels of total WBC count. The extract was found to be an effective immunostimulant agent.

Keywords

Desmodium triflorum SRBCs suspension levamizole immunostimulant

Article Details

How to Cite
Garlapati Ushakiran, & Sangamesh B puranik. (2022). Immunomodulatory effect of leaf aqueous extract of Desmodium triflorum . International Journal of Research in Pharmacology & Pharmacotherapeutics, 11(1), 1-11. Retrieved from https://ijrpp.com/ijrpp/article/view/416

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