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Aim: To establish the strength of association between intraoperative application of Mitomycin C (MMC) in pediatric Dacryocystorhinostomy (DCR) and its surgical outcomes., thereby determining the role of MMC in improving the success rate of DCR surgery in pediatric population.

Materials & Methods: It is a prospective observational study conducted at Gandhi Hospital Hyderabad & Sarojini Devi Regional Eye Institute Hyderabad. 60 Eyes of 60 children of different age groups ranging from one month to 15 years were included in the study. Our study population was the paediatric patients attending the out-patient department. They were recruited after informed consent was obtained from the patient’s guardians and after getting confirmation from them for willingness for follow-up as per study guide lines. Those patients who were requiring DCR surgery were taken up for external Dacryocystorhinostomy in which 30 patients were randomly selected and subjected to cotton pledget soaked in topical MMC (0.002% or0.2mg/ml) for 2 minutes. The study was conducted from Nov-2018 till Oct-2020.

Result: There was statically significant success rate of primary external DCR with the use of inta-operative MitomycinC over DCR without MitomycinC in congenital Nasolacrimal Duct Obstruction.

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How to Cite
Dr. D Kesava Rao, & Dr. K Ravishekar Rao. (2021). Role of Mitomycin C intraoperatively in improving the success rate of DCR surgery in paediatric population. International Journal of Research in Pharmacology & Pharmacotherapeutics, 10(3), 286-291. Retrieved from


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