Article Sidebar

Submitted
May 30, 2021
Published
May 30, 2021
Download
PDF
Statistic
Read Counter : 83 Download : 46

Main Article Content

Abstract

The aim of the study is to determine the outcome of women referred for Colposcopy and directed biopsy with abnormal pap smears and smears showing persistent inflammation. Cervical cancer is a significant health problem worldwide among women. Cancer cervix is the most common cancer in developing countries. It is considered as preventable cancer since there is availability of screening method and effective diagnostic and therapeutic procedures. Despite the accuracy and efficacy of cervical cytology in detecting and diagnosing cervical neoplasia, it must remain a screening technique with further evaluation based on histologic diagnosis. The objectives of the study are To study the Colposcopic features of abnormal pap smears and persistent inflammatory cellular changes on pap smear, To localize the lesion by Colposcopy and obtain a biopsy, To assess the prevalence of CIN in the study group. To correlate pap smear findings with colposcopic findings, To study the epithelial cell abnormalities by colposcopic biopsy of abnormal areas in such cases, To determine the existence of significant cervical intraepithelial lesion or invasive carcinoma in patients with persistent inflammatory pap smear. The present study is undertaken to evaluate the role of cytology and Colposcopic guided biopsy in diagnosing neoplastic cervical lesions.

Keywords

Colposcopy Cervical cancer Cervical cytology Histologic diagnosis Pap smear

Article Details

How to Cite
Dr.Mohammed Imran Ali. (2021). A study on colposcopic directed biopsy in early detection of malignant lesions of cervix. International Journal of Research in Pharmacology & Pharmacotherapeutics, 5(4), 377-387. https://doi.org/10.61096/ijrpp.v5.iss4.2016.377-387
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. [1]. World health organization fact sheet no 297; cancer, Retrieved 2006, 2007 – 12 - 01.
  2. [2]. Rejendra A Kalkar, Yogesh Kulkarini. Screening for cervical cancer: an overview. Obstet Gynecol India 56(2), 2006.
  3. [3]. Mohammed Shaoaib Khan, Fohadiya Yasin Raja at el. Pap smear Screening for Precancerous conditions of the cervical cancers. Pak J. Med. Res.; 44(3), 2005, 111-3.
  4. [4]. Globocan 2002 data base table by cancer, Retrieved 10, 2008, 26.
  5. [5]. Kent A,HPV vaccination and testing, Reviews in Obstetrics and gynaecology 3, 2010, 33 - 34.
  6. [6]. DiBonito L, Falconieri G, Tomaic G, Colautti I, Bonifacio D, Dudine S. Cervical Cytopathology: An evaluation of its accuracy based on Cytohistologic comparison. Cancer 72, 1993, 300-6.
  7. [7]. Wilkinson EJ, Paponicolou smear and screening for cervical neoplasia. Obstet Gynecol 35, 1990, 817-25.
  8. [8]. Gay JD, Donaldson LD, Goellner JR. False negative results in cervical cytological studies. Acta Cytol 29, 1985, 1043-6.
  9. [9]. Moss F, Blaser MJ. Mechanism of Disease: Inflammation and origin of cancer/. Nat Clin Pract Oncol 2, 2005, 907.
  10. [10]. Seckin NC, Turhan NO, Ozmen S, Erssan F, Avoar F, Ustun H . Routine colposcopic evaluation of patients with persistent inflammatory cellular changes on pap smear. Int Gynecol Obstet 59, 1997, 25-9.
  11. [11]. McLachlan N, Patwardhan JR, Ayer B, Pacey NF. Management of suboptimal cytological smears. Acta Cytol 38, 1994, 531-6.
  12. [12]. Parashari A, Singh V, Gupta MM, Satyanarayana L, Chattopadhya D, Sodhani P, et al. Significance of inflammatory cervical smears. APMIS 103, 1995, 273-8.
  13. [13]. ACOG Practice Bulletin. Clinical management guidelines for Obstetrician and Gynecologist Cervical Cytology screening Obstet Gynecol 102, 2003, 417-27.
  14. [14]. Walker EM, Dodgson J, Duncan ID. Does mild atypia on a cervical smear warrant further investigation? Lancer 2, 1986, 772-3.
  15. [15]. Giles JA, Hudson EA, Crow J, William D, Walker P. Colposcopic assessment of the accuracy of the cervical cytology screening. BMJ 296, 1988, 1099-102.
  16. [16]. Soutter WP, Wisdom S, Brough AK, Monaghan JM. Should patients with mild atypia in cervical smear be referred for colposscopy? Br J Obstet Gynecol 93, 1986, 70-4.
  17. [17]. Duncan ID. Guideline for clinical practice and program management. Oxford: National Coordinating Network, NHS cervical screening programme, 1993.
  18. [18]. WHO .Management of sexually transmitted diseases at district and PHC level; Regional publication SERO; 25, 1999.
  19. [19]. (Kurman RJ, Malkasian GD Jr. Sedlis A, Solomon D. From Papanicolaou to Betheda: The rationale for a new cervical cytologic classification. Obstet Gynecol 77, 1991, 779-82.
  20. [20]. Guldeniz Aksan-Desteli, Turkan Gursu , Cem Murat Baykal, Is the Loop Electrosurgical Excision Procedure Necessary for Minor Cervical Cytological Abnormalities?, Asian Pacific Journal of Cancer Prevention, 15, 2014, 305-308.
  21. [21]. Marchand L, Van Dinter M, Mundt M, Dingel W, Klein G Current cervical cancer screening practices of Dane county, Wsconsin Primary care clinicians. WMJ 102, 2003, 3540.