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The aim of the study is to determine the outcome of women referred for Colposcopy and directed biopsy with abnormal pap smears and smears showing persistent inflammation. Cervical cancer is a significant health problem worldwide among women. Cancer cervix is the most common cancer in developing countries. It is considered as preventable cancer since there is availability of screening method and effective diagnostic and therapeutic procedures. Despite the accuracy and efficacy of cervical cytology in detecting and diagnosing cervical neoplasia, it must remain a screening technique with further evaluation based on histologic diagnosis. The objectives of the study are To study the Colposcopic features of abnormal pap smears and persistent inflammatory cellular changes on pap smear, To localize the lesion by Colposcopy and obtain a biopsy, To assess the prevalence of CIN in the study group. To correlate pap smear findings with colposcopic findings, To study the epithelial cell abnormalities by colposcopic biopsy of abnormal areas in such cases, To determine the existence of significant cervical intraepithelial lesion or invasive carcinoma in patients with persistent inflammatory pap smear. The present study is undertaken to evaluate the role of cytology and Colposcopic guided biopsy in diagnosing neoplastic cervical lesions.


Colposcopy Cervical cancer Cervical cytology Histologic diagnosis Pap smear

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How to Cite
Dr.Mohammed Imran Ali. (2021). A study on colposcopic directed biopsy in early detection of malignant lesions of cervix. International Journal of Research in Pharmacology & Pharmacotherapeutics, 5(4), 377-387. Retrieved from


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