Article Sidebar

Submitted
May 21, 2021
Published
May 21, 2021
Download
PDF
Statistic
Read Counter : 107 Download : 67

Main Article Content

Abstract

Okra (Abelmochus esculentus) is an economically important vegetable crop grown in tropical and subtropical parts of the world. In the present we investigated the phytochemical analysis of aqueous and ethanol extract of okra and the invivo antidiabetic effect of aqueous extract of Abelmoschus esculentus against Alloxan induced diabetic rat.  The standard drug glibenglimide (5 mg/kg) and Abelmoschus esculentus (150 mg/kg) were dissolved in water in given orally.  The blood glucose levels of rats were noted at regular intervals of time. A gradual decrease in the blood glucose levels was observed by regular feeding of “okra” Abelmoschus esculentus (ladies finger) fruit extract for about twelve days.

Keywords

Abelmoschus esculents Diabetes study on rats Blood sugar level

Article Details

How to Cite
Agnes Jenitha X, & Kanimozhi R. (2021). Evaluation of phytochemicals and anti-diabetic activity of abelmoschus esculentus. International Journal of Research in Pharmacology & Pharmacotherapeutics, 5(2), 142-152. https://doi.org/10.61096/ijrpp.v5.iss2.2016.142-152
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. [1]. Vetrichelvan T, Jagadeesan M, Uma Devi B, A, (2002) Antidiabetic activity of alcohol of Celosia argentea Linn. Seeds in rats. Biol Pharm Bull. P (28).
  2. [2]. Wild S, Roglic G, Green A, Sicree R, King H, (2004). "Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030"Vol (27).
  3. [3]. Jump up (2012) RSSDI textbook of diabetes mellitus. New Delhi: Jaypee Brothers Medical Publishers. p. 235.
  4. [4]. Kitabchi A E, Umpierrez G E, Miles J M, Fisher J N (2009). "Hyperglycemic crises in adult patients with diabetes". Diabetes Care, Vol (32).
  5. [5]. Cooke D W, Plotnick L (2008). "Type 1 diabetes mellitus in Pediatrics". Pediatr Rev Vol (29).
  6. [6]. American, Association, (2013). "Economic costs of diabetes in the U.S. p. 1033.
  7. [7]. Shoback, David G, Gardner, Dolores, (2011). Greenspan's basic & clinical endocrinology. Vol (17).
  8. [8]. Kim E. Barrett, (2012). Ganong's review of medical physiology. Vol (24).
  9. [9]. Grubben G J H, & Denton O A, (2013) PROTA (Plant Resources of Tropical Africa / Ressources végétales de l’Afrique tropicale), Wageningen, Netherlands.
  10. [10]. Robert K. Murray, (2012). Harper's illustrated biochemistry Vol (29).
  11. [11]. Sarwar N, Gao P, Seshasai S R, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor D A, Selvin E, Stampfer M, Stehouwer C D, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray K K, Danesh J(2010). "Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies". P. 375.
  12. [12]. Rippe, Richard S, Irwin, James M. (2010). Manual of intensive care medicine Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 549.
  13. [13]. Cash, Jill (2014). Family Practice Guidelines. Springer. p. 396.
  14. [14]. Vijan, S (2010). "Type 2 diabetes". Annals of Internal Medicine, Vol (152).
  15. [15]. Trease GE and Evans WC, a textbook of Pharmacognecy. 14th ed.Bailliere Tindall Ltd., London, 2013; 832.
  16. [16]. Trider, P. (1969)Estimation of glucose c ann. Clin. Biochem., 6:24.
  17. [17]. Bunn, 1981Bunn.H.F (1981), Estimation of glycylated Hemoglobin (HbA1method) Diabetes, 30:613-617
  18. [18]. Misra and Fridovich (2000). Superoxide dismutase was assayed according to the method.
  19. [19]. Takahara (2000) Catalase was assayed according to the method
  20. [20]. Okhawa (1979). The extent of lipid peroxidation was estimated according to the method
  21. [21]. Ramiladevi M and manonaran A (2011) phytochemical investigation of erithrina in variegate leaves. Journal of chemical and phytochemical and pharmaceutical research 3 (6) p. 166-172.
  22. [22]. Sue G, Peng L, L, (2004) An improved method for the analysis of major antioxidants of Hibiscus esculentus Linn. Journal of Chromatography Vol (1): P 17–24.