Main Article Content

Abstract

Objective

The in vitro studies on phytochemical analysis and antioxidant activity of Heliotropium indicum Lin. (Boraginaceous) was evaluated by different assaying.


Methods

The in vitro antioxidant activity was evaluated for total antioxidant activity, 1,1-diphenylhydrazyl (DPPH) radical scavenging and hydroxyl radical scavenging activity.


Results

The percentage of inhibition of the total antioxidant activity, DPPH radical scavenging and hydroxyl radical scavenging activity was varying from ethanol and aqueous extracts.


Conclusion

The results clearly indicate that the ethanol and aqueous leaf extracts of the study species is effective in scavenging free radicals and has the potential to be a powerful antioxidant.

Keywords

Heliotropium Indicum Antioxidant Activity Phytochemicals DPPH Activity

Article Details

How to Cite
Dr. Jayachitra J, & Bharathi M. (2021). In vitro studies on phytochemical analysis and antioxidant activity of Heliotropium indicum linn. International Journal of Research in Pharmacology & Pharmacotherapeutics, 5(2), 108-114. https://doi.org/10.61096/ijrpp.v5.iss2.2016.108-114

References

  1. [1]. Narayanaswami N and Balakrishnan KP (2011). Evaluation of Some Medicinal Plant for their antioxidant properties. Intl. J. Pharm. Tech. Res.., 3: 381-385.
  2. [2]. Mon MM Mau SS and Oo ZK, (2011). Quantitative determination of free radical scavenging activity and antiumour activity of some Myanmar herbal plant. World Aca. Sci. Eng. The. 51: 523-529.
  3. [3]. Satheeshkumar D, Kottaiumuthu A, Anton smith A and Manavalan R, (2010). Free Radical Scavenging Activity Of Various Extract of Whole Plant of Mucuna Pruriens (Linn): An In Vitro Evaluation. J. Pharm.Res., 3: 718-721
  4. [4]. Forombi, E. (2003). African indigenous plants with chemotherapeutic potentials and biotechnological approach to the production of bioactive prophylactic agents. African J. Biotech. 2: 662-671.
  5. [5]. Boominathan, M. and Ramamurthy, V. (2009). Antimicrobial activity of Heliotropium indicum and Coldenia procumbens. J. Ecobiol., 24 (1): 11 – 15.
  6. [6]. Ogunbinu AO, Flamini G, Cioni PL, Adebayo MA, Ogunwande IA., (2009). Constituents of Cajanus cajan (L.) Millsp., Moringa oleifera Lam., Heliotropium indicum L. and Bidens pilosa L. from Nigeria. Natural Product Communications; 4(4):573-578.
  7. [7]. Akinlolu Abdulazeez Adelaja, Ayoola M. D. , Otulana J. O., Akinola O. B. , Abimbola Olayiwola & A. B. Ejiwunmi.,(2008)., Evaluation Of The Histo - Gastroprotective And Antimicrobial Activities Of Heliotropium Indicum Linn (Boraginaceae., Malaysian Journal Of Medical Sciences, Vol. 15, No. 3, Pp(22-30).,
  8. [8]. Nusrat Ahmed Mourin, Tasnuva Sharmin,Sharmin Reza Chowdhury, Farhana Islam, Mohammad S. Rahman, MohammadA. Rashid, (2013). Evaluation of bioactivities of Heliotropium indicum, a medicinal plant of Bangladesh. The pharma innovation journal;2 (2).
  9. [9]. Auddy B, Ferrira M, Blasina F, Lafon L, Arredondo F, and Dajas F (2003).Screening Of Antioxidant Activity Of Three Indian Medicinal Plants Traditionally Used For The Management Of Neurodegenerative Disease. Journal of Ethanopharmacology; 84:131-138.
  10. [10]. Kokate ck., (2001), pharmacohnosy. 16 th Edu , Nirali Prakhasan, Mumbai, India.
  11. [11]. Shimada, K., Fujikawa, K., Yahara, K., & Nakamura, T. (1992). Antioxidative Properties Of Xanthan On The Autoxidation Of Soybean Oil In Cyclodextrin Emulsion. Journal of Agricultural and Food Chemistry, 40: 945-948.
  12. [12]. Proeto P. Pinda M., Aguilar M., (1999). Septrophotometric Quantitation Of Antioxidant Capcity Through The Formation Of A Phosphomolybdenum Complex: Specific Application To The Determination Of Vitamin E; Analytical Biochemistry, 269: 337-341.
  13. [13]. klein sm., cohen g., cederaum ai (1991). Production of formaldehyde during metabolism of dimethyl sulphoxide by hydroxyl radical generating system. Biochemistry, 20: 6006-6012.
  14. [14]. Dasarapu santhosha, Alluri Ramesh, emandi hemalatha , malothu nagulu., (2015). Phytochemical Screening and anti-oxidant activity of ethanolic extract of Heliotropium Indicum.,International Research Journal Of Pharmacy .,6 (8).,
  15. [15]. Obayed Ullah M, Sultana S, Haque A, Tasmin S., (2009), Eur J Sci Res, Antimicrobial, Cytotoxic And Antioxidant Activity Of Centella Asiatica, 3, 2009, 260-264.
  16. [16]. A.Philips, S. Philips ,V. Arul , .Padmakeerthiga, V. Renju, S. Santha.,( 2010) J. Pharm Sci Res .,Vol . 2 322-328.