Article Sidebar

Submitted
May 16, 2021
Published
May 16, 2021
Download
PDF
Statistic
Read Counter : 41 Download : 40

Main Article Content

Abstract

Malaria and HIV are a major public health problem in developing countries. Our study was a prospective study to find the incidence of malaria during HIV infection in Bamako at the    national referral and teaching hospital “Point G” from May 1st, 2006 to February 28th, 2007.  Among 212 patients hospitalized or followed as patients with HIV positive by rapid tests: Immuno Comb II HIV 1/2 (Organics, Strasbourg, France) and genie II HIV 1/2 (Sanofi Diagnostics Pasteur, France); 46 patients had a positive malaria test (21.6%). Theses coinfected patients (Plasmodium/ HIV) have been enrolled in the study.  The age average was 34.4 ± 9.4 years. The sex ratio was 0.7. The patient majority had a CD4 rate less than 200 cells/mm3. The HIV 1 infection was predominant in 45 patients (97.6%). The risk of exposure to the complicated malaria during HIV infection was higher in patients with the AIDS stage than seropositive patients (p = 0.04 fisher). The risk of exposure to moderate anemia during HIV infection was higher in patients with the AIDS stage than seropositive patients (p = 0.01 fisher). The majority of patients did not use preventive measures which are 71.7%. The hospital case lethality was 34%. We can confirm that Malaria has been relatively frequently during the HIV infection in Mali. Malaria chemoprophylaxy combined to bed nets use by HIV/AIDS patient should improve the morbidity and mortality due to this disease.

Keywords

Malaria HIV/AIDS Mali

Article Details

How to Cite
Dembele JP, Oumar AA, Djibril N, Keita PM, Ba M, Garba MN, Maiga I, & Dao S. (2021). Prevalence and treatment of malaria during the AIDS infection in hospital area of Bamako, Mali. International Journal of Research in Pharmacology & Pharmacotherapeutics, 5(1), 30-35. https://doi.org/10.61096/ijrpp.v5.iss1.2016.30-35
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. [1]. World Health Organization (WHO). (1998) le paludisme, N° 94, révisé Octobre (in French)
  2. [2]. UNAIDS/WHO (2008). Le point sur l’épidémie de SIDA, (in French). www.unaids.org.
  3. [3]. Severov MV, Comolet T, Magassouba N,Barry M, et Diallo AAS (2000). Epidémiologie du paludisme grave chez l’adulte à Conakry (Guinée): implication pour la stratégie et le contrôle. Médecine Afrique Noire; 47: 65-71.
  4. [4]. Saissy JM, Cellard-Peyle F, Vitris M, Demazière J, Gaye M, Poli L, et al.(1994) Paludisme grave en zone d’endémie saisonnière africaine, comparaison des formes de l’adulte et de l’enfant et valeur pronostrique des cytokines. Presse Med, 23: 1426-1430.
  5. [5]. French N, Gilks C F (2000). Some controversies in tropical medicine and hygiene. HIV and malaria, do they interact? Trans R Soc Trop MED Hyg; 94 (3): 233-7.
  6. [6]. Baudon D, Louis FJ, Market G (1996). En Afrique, le paludisme urbain est le paludisme de demain. Med trop, 56: 323-325.
  7. [7]. Samake S, Traore SM, Ba S, Dembele E, Diop M, Mariko S, et Libité PR(2012). Enquête démographique de la santé Mali-IV. EDS-IV. Bamako, 410P (in French): http://www.cspro.org/pubs/pdf/FR199/FR199.pdf
  8. [8]. ZAKARIA S (2001). Dépistage du VIH au CNTS de Bamako de 1993 à 1999. Thèse de doctorat en Pharmacie, Université de Bamako, (in French). http://www.keneya.net/cgi-bin/isis/wxis/fmpos/bases/
  9. [9]. Charmot G, Simon F(1990). HIV infection and malaria. Rev Prat; 40 (23): 2141-3.
  10. [10]. French N, Nakiyingi J, Lugada E, Watera C, Withworth J A, Gilks C F(2002). Increasing rates of malarial fever with deteriorating immune status in HIV-1 infected Ugandan adults. AIDS, 15 (7): 899-906.
  11. [11]. Olivier T, Peaufique-Olivier M, Delmont J, Sirimbo M, Vohito JA, Testa J, et al.(1991) Virus de l’immunodéficience humaine (VIH) et paludisme chez des donneurs de sang en République Centrafricaine. Médecine Afrique Noire, 38 (3) - 175-79.
  12. [12]. Francesconi P, Fabiani M, Dente M G, Lukwiya M, Okwey R, Ouma J, et al.(2001) HIV, malaria parasites, and acute febrile episodes in Ugandan adults: a case control study. AIDS; 15 (18): 2445-50.
  13. [13]. Doumbo O, Ouattara N, Koita O,Maharaux A,Toure YT,Traore SF et Quilici M(1989). Approche écogéographique du paludisme en milieu urbain: la ville de Bamako au Mali. Bull Ecol hum; 8 (3); 3-15.
  14. [14]. 14. World Health Organization (2000). Severe falciparum malaria. Trans R Soc Trop Med Hyg; 94: S1-90.
  15. [15]. Onyenekwe CC, Ukibe N, Meludu SC, Ilika A, Aboh N, Ofiaeli N, et al.(2007). Prevalence of malaria as co-infection in HIV-infected individuals in a malaria endemic area of southeastern Nigeria. J vector Borne Dis; 44 (4): 250-4.
  16. [16]. Diallo AH, Ki-zerbo G, Sawadogo AB et Guiguemde TR (2004). Paludisme grave et infection à VIH chez l’adulte à Bobo-dioulasso, Burkina Faso. Med Trop, 64, 345-50.
  17. [17]. Oumar AA , Dao S, Kamsi NA, Sogoba D, Rhaly A, et Diallo A(2008). Etude épidémiologique clinique et économique du VIH/SIDA dans le service des maladies infectieuses de l’hôpital du point G. Louv Med, 127 (4) :125-129.
  18. [18]. Diallo D, Baby M, Dembele M, Keita A, Sidibe A T, Cisse I A et al. (2002) Fréquence, facteurs de risque et valeur pronostique de l’anémie associée au VIH/SIDA chez l’adulte au Mali Bull Soc Pathol Exot ; (96) :123-7.
  19. [19]. Leaver RJ HAILZ and Kwatters DA (1990). HIV and cerebral malaria. Trans R soc, Trop Med hyg; 84 (2):201.
  20. [20]. BiapoK (2004).Coinfection paludisme et VIH/SIDA dans les services de médecine interne et des maladies infectieuses de l’hôpital National du Point G. Thèse de doctorat en Médecine, Université de Bamako.(In french) http://www.keneya.net/cgi-bin/isis/wxis/fmpos/bases/
  21. [21]. Greenberg AE, Bahwe Y, Nekwei W, Ryder R, Perriens J, Nsimba K , et al.(1990) Incidence of malaria efficacy of oral quinine in patients recently infected with human immunodeficiency virus in Kinshasa, Zaire. J Infect; 21 (2): 167-73.