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Abstract
The COVID-19 pandemic represents an unprecedented global healthcare challenge. Aside from being a primary respiratory
disease, acute ischemic stroke has emerged as a complication of the disease. There are many similarities in the risk factors for
severe COVID-19 as well as ischemic stroke, which underscore the complex relationship between these two conditions. Acute
ischemic stroke in patients with COVID-19 may be due to usual causes such as atherosclerosis, hypertension, and atrial
fibrillation. Approximately 5% of hospitalized patients with covid -19 suffer from stroke with over 80% of them being ischemic
stroke. Rapid assessment and time-sensitive interventions required for optimum outcomes in acute stroke care have been
complicated by COVID-19. In this review, however, we focus on mechanisms of stroke that appear to be directly related to
COVID-19, the clinical features of COVID-19 patients who develop ischemic stroke, and in addition we have discus the
management approaches of acute ischemic stroke in COVID-19 patients.