Main Article Content
Abstract
Background
Periodic prescription analysis is one of the methods to assess drug utilization and rationality of prescribing. It should be regularly conducted to improve the quality of prescription and curb the menace of irrational prescribing which has become a worldwide problem.
Objectives
To analyze the rationality status of prescriptions and drug utilization pattern in inpatients admitted in a tertiary care hospital.
Materials and Methods
The present observational retrospective study was carried out in inpatients of Medicine, Surgery, Gynaecology, Pediatrics, Skin, Orthopaedics and Psychiatric departments of our tertiary care hospital over a period of three months during which data of 200 patients were collected. The age, sex and diagnosis of the patients were noted. The rationality of prescriptions was evaluated using WHO core indicators of drug utilization.
Results
Two hundred prescriptions were analysed in which 1036 drugs were prescribed. Mean number of drugs per prescription was 5.18. In our study, 75.97% drugs were prescribed by generic names and drugs from EDL were 75.48%. Dosage forms used were mostly oral (60.71%). Infectious diseases were the most common illnesses (19.5%) followed by diseases of respiratory system. The most common drug groups prescribed were antimicrobials, analgesics & anti-inflammatory drugs, GIT , multivitamins and minerals. The incidence of poly-pharmacy was also common with maximum number of prescriptions (36.5%) having five drugs per prescription.
Conclusion
Prescription analysis is an important measure to improve the quality of care afforded by the hospitals. Establishment and implementation of appropriate clinical guidelines, use of essential medicines list, continuing medical education and regular update to the clinicians will help in implementing the principles of rational pharmacotherapeutics.
Keywords
Article Details
References
- [1]. 2014, http://apps.who.int/medicinedocs/en/d/Js4876e.
- [2]. U. Bergman, I. Christenson, B. Jansson, and B. E. Wiholm, “Auditing hospital drug utilisation by means of defined daily doses per bed-day. A methodological study,” European Journal of Clinical Pharmacology, 17(3), 1980, 183–187.
- [3]. Promoting Rational Use of Medicines: Core Components-WHO Policy perspectives on medicine, No. 005, September 2002. Essential medicines and Health Products Information Portal. A World Health Organization Resource. 2014.
- [4]. Strom BL, Stephan EK, editors. Pharmacoepidemiology. Wiley-Blackwell: John Wiley and Sons, English; 5, 2005.
- [5]. 5. Patel Neha, Shah Shreya, Asari Pratik, Amin Anand. Prescription auditing and drug utilization pattern in indoor patients of pediatrics department. Int J Cur Res Rev 8(23), 2016.
- [6]. Shikha Mishra, Parag Sharma. Prescription audit and drug utilization pattern in a tertiary care teaching hospital in Bhopal. Int J Basic Clin Pharmacol. 5(5), 2016, 1845-1849.
- [7]. Potharaju HR, Kabra SG. Prescription audit of outpatient attendees of secondary level government hospitals in Maharashtra. Indian J Pharmacol 43, 2011, 150-6
- [8]. Nishita H. Darji, et al.: Prescription audit in a tertiary care hospital. Journal of Clinical & Experimental Research 3(2), 2015.
- [9]. Afroz Abidi*, Surabhi Gupta, Saurabh Kansal. Prescription auditing and drug utilization pattern in tertiary care teach- ing hospital in western UP. Int J Basic Clin Pharmacol. 1(3), 2012, 184-190 .
- [10]. Vishwanath M., Reddy NS., Devadas S. Assessment of drug uti- lization in hospitalized children at a tertiary care teaching hospi- tal. J. Chem.Pharm. Res. 6(2), 2014, 592-598.
- [11]. Saurabh MK, Yadav AK, Gupta P. Comparative study of pre- scribing behaviors of government doctors of teaching hospital and private practitioners in Jhalawar City (Rajashtan). J.Pharm. Sct. & Res., 2(4), 2010, 208-215.
- [12]. Kastury N, Singh S, Ansari KU. An audit of prescription for rational use of fixed dose drug combinations. Indian J Pharmacol 31, 1999, 367-9.
- [13]. Chakrabarti A. Prescription of fixed dose combination drugs for diarrhoea. Indian J Med Ethics 4, 2007, 165-7.
- [14]. Hutin YJF, Hauri AM, Armstrong GL. Use of injections in healthcare setting worldwide, 2000: literature review and regional estimates. BM] 327, 2003, 1075-9.
- [15]. Akhilesh G Sukhlecha, Shuchita Vaya, Ghanshyam G Parmar, KD Chavda. Pattern of drug utilization in surgical outpatient department of a teaching hospital located in western India. International Journal of Medical Science and Public Health 4(9), 2015.
References
[1]. 2014, http://apps.who.int/medicinedocs/en/d/Js4876e.
[2]. U. Bergman, I. Christenson, B. Jansson, and B. E. Wiholm, “Auditing hospital drug utilisation by means of defined daily doses per bed-day. A methodological study,” European Journal of Clinical Pharmacology, 17(3), 1980, 183–187.
[3]. Promoting Rational Use of Medicines: Core Components-WHO Policy perspectives on medicine, No. 005, September 2002. Essential medicines and Health Products Information Portal. A World Health Organization Resource. 2014.
[4]. Strom BL, Stephan EK, editors. Pharmacoepidemiology. Wiley-Blackwell: John Wiley and Sons, English; 5, 2005.
[5]. 5. Patel Neha, Shah Shreya, Asari Pratik, Amin Anand. Prescription auditing and drug utilization pattern in indoor patients of pediatrics department. Int J Cur Res Rev 8(23), 2016.
[6]. Shikha Mishra, Parag Sharma. Prescription audit and drug utilization pattern in a tertiary care teaching hospital in Bhopal. Int J Basic Clin Pharmacol. 5(5), 2016, 1845-1849.
[7]. Potharaju HR, Kabra SG. Prescription audit of outpatient attendees of secondary level government hospitals in Maharashtra. Indian J Pharmacol 43, 2011, 150-6
[8]. Nishita H. Darji, et al.: Prescription audit in a tertiary care hospital. Journal of Clinical & Experimental Research 3(2), 2015.
[9]. Afroz Abidi*, Surabhi Gupta, Saurabh Kansal. Prescription auditing and drug utilization pattern in tertiary care teach- ing hospital in western UP. Int J Basic Clin Pharmacol. 1(3), 2012, 184-190 .
[10]. Vishwanath M., Reddy NS., Devadas S. Assessment of drug uti- lization in hospitalized children at a tertiary care teaching hospi- tal. J. Chem.Pharm. Res. 6(2), 2014, 592-598.
[11]. Saurabh MK, Yadav AK, Gupta P. Comparative study of pre- scribing behaviors of government doctors of teaching hospital and private practitioners in Jhalawar City (Rajashtan). J.Pharm. Sct. & Res., 2(4), 2010, 208-215.
[12]. Kastury N, Singh S, Ansari KU. An audit of prescription for rational use of fixed dose drug combinations. Indian J Pharmacol 31, 1999, 367-9.
[13]. Chakrabarti A. Prescription of fixed dose combination drugs for diarrhoea. Indian J Med Ethics 4, 2007, 165-7.
[14]. Hutin YJF, Hauri AM, Armstrong GL. Use of injections in healthcare setting worldwide, 2000: literature review and regional estimates. BM] 327, 2003, 1075-9.
[15]. Akhilesh G Sukhlecha, Shuchita Vaya, Ghanshyam G Parmar, KD Chavda. Pattern of drug utilization in surgical outpatient department of a teaching hospital located in western India. International Journal of Medical Science and Public Health 4(9), 2015.