Main Article Content
Abstract
Background
Irrational prescribing of antibiotics leads to bacterial resistance, increased cost of therapy and serious adverse drug reactions. Our study aims at analyzing the use of antibiotics in hospitalized patients with infections in a tertiary care hospital of a semi urban area.
Methods
A total of 100 inpatient case records treated with antibiotics were chosen. The demographic data, disease data and the utilization of different AMAs were analyzed.
Results
A total of 310 prescriptions of antibiotics were noted in the study in 100 patients (i.e. – an average of 3.1antibiotics/patient). Metronidazole (21%), Cefotaxime (13%) and Gentamicin (13%) were the most common antibiotics used. Most common infections were involving genitourinary tract and respiratory system. Culture and sensitivity were done in 18 patients. Pipericillin +Tazobactum was the most common FDC prescribed in our study. 91% of patients were completely recovered from illness.
Conclusion
The use of combination of antibiotics should be restricted and narrowed down to specific agents. The antibiotic prescribing guidelines should be strictly followed in patient care. With appropriate and effective use of antibiotics, patient care may be improved and antibiotic resistance may be avoided.
Keywords
Article Details
References
- [1]. COOKE D, SaltER aj, Phillips J. antimicrobial MISUSE, antibiotic policies and information resources. J antimicrobials chemother 6, 1980, 435-43.
- [2]. Hirschman SZ, Meyers BR, Bradbury K, MehlB. Use of antimicrobial agents in a university teaching hospital. Arch Intern med 148, 1988, 2001-7.
- [3]. Lim VKE, Cheong YM, sulciman. Pattern OF antibiotic USAGE IN hospitals in malaysia. singapore medical journal 34, 1993, 525-528.
- [4]. Esposito S,Leone S. Antimicrobial treatment OF ICU infections including the role of the infectious disease specialist. Int J Antimicrob Agents. 29, 2007, 494-500. prescribing
- [5]. Srishyla MA, Melendy S, Jahns B, et al. An exploratory analysis of medical utilization in a medical intensive care unit. Crit care med, 21(a), 1993, 319-23.
- [6]. McCafferty JA, HANG sdr. An audit of restricted antibiotic use in a general hospital. New Zealand medical journal 101, 1988, 210-211.
- [7]. Straand J. How often do general practitioners prescribe antibiotics for ottitis media and the most common respiratory tract infections? Norwegian journal of epidemiology 11, 2001, 67-72.
- [8]. Erah PO, Olumide GO, OKhamafe AO. Prescribing practitices in two health care facilities in warri, southern higeria: A comparative study. Tropical journal of pharmaceutical research 2, 2003, 175-182.
- [9]. Shanker PR, Dubey AK Rana MS. Drry utilization with special reference to antimicrobials in a sub health post in western Nepal. Journal of Nepal health research council 3, 2005, 65-69.
- [10]. Barman A, Ahmad J Ahmed AV. Treatment pattern of watery diarrhea at primary health care level of Bangladesh. Teachers association journal 7(2), 1994, 80-82.
- [11]. SULTAN-Ul-Alam M, Barna PC, Islam AFMS. A survey of the pattern of drug utilization for watery diarrhea at primary division. Hygeia 7(1), 1993, 15-18.
- [12]. Islam MN, Astudy on prescribing pattern of antibiotics by registered medical practitioners in private chamber in a selected district, Bangladesh department of public health and hospital administration, NIPSOM, Bangladesh, 59, 1994.
- [13]. Ballin JC, Dykes MHM, Jeromc JB, Kojman ME. In comment. Reasons for increase in antibiotic usage. Journal of American medical association 227, 1974, 1029-1030.
References
[1]. COOKE D, SaltER aj, Phillips J. antimicrobial MISUSE, antibiotic policies and information resources. J antimicrobials chemother 6, 1980, 435-43.
[2]. Hirschman SZ, Meyers BR, Bradbury K, MehlB. Use of antimicrobial agents in a university teaching hospital. Arch Intern med 148, 1988, 2001-7.
[3]. Lim VKE, Cheong YM, sulciman. Pattern OF antibiotic USAGE IN hospitals in malaysia. singapore medical journal 34, 1993, 525-528.
[4]. Esposito S,Leone S. Antimicrobial treatment OF ICU infections including the role of the infectious disease specialist. Int J Antimicrob Agents. 29, 2007, 494-500. prescribing
[5]. Srishyla MA, Melendy S, Jahns B, et al. An exploratory analysis of medical utilization in a medical intensive care unit. Crit care med, 21(a), 1993, 319-23.
[6]. McCafferty JA, HANG sdr. An audit of restricted antibiotic use in a general hospital. New Zealand medical journal 101, 1988, 210-211.
[7]. Straand J. How often do general practitioners prescribe antibiotics for ottitis media and the most common respiratory tract infections? Norwegian journal of epidemiology 11, 2001, 67-72.
[8]. Erah PO, Olumide GO, OKhamafe AO. Prescribing practitices in two health care facilities in warri, southern higeria: A comparative study. Tropical journal of pharmaceutical research 2, 2003, 175-182.
[9]. Shanker PR, Dubey AK Rana MS. Drry utilization with special reference to antimicrobials in a sub health post in western Nepal. Journal of Nepal health research council 3, 2005, 65-69.
[10]. Barman A, Ahmad J Ahmed AV. Treatment pattern of watery diarrhea at primary health care level of Bangladesh. Teachers association journal 7(2), 1994, 80-82.
[11]. SULTAN-Ul-Alam M, Barna PC, Islam AFMS. A survey of the pattern of drug utilization for watery diarrhea at primary division. Hygeia 7(1), 1993, 15-18.
[12]. Islam MN, Astudy on prescribing pattern of antibiotics by registered medical practitioners in private chamber in a selected district, Bangladesh department of public health and hospital administration, NIPSOM, Bangladesh, 59, 1994.
[13]. Ballin JC, Dykes MHM, Jeromc JB, Kojman ME. In comment. Reasons for increase in antibiotic usage. Journal of American medical association 227, 1974, 1029-1030.