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May 1, 2021
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May 1, 2021
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Abstract

Background


Chronic Suppurative Otitis Media (CSOM) is a serious healthcare concern worldwide, especially in developing countries like India despite the advances in healthcare facilities. India’s prevalence of CSOM is 7.8% which is high and this may be related to frequent upper respiratory tract infections and poor socio-economic conditions. In general practice, the therapeutic approach for ENT infections is nearly empirical and the main aim of physicians is to treat as specifically as possible, while covering the most likely pathogens. This study was undertaken to evaluate the prescribing pattern of antimicrobials in CSOM patients in a tertiary care hospital. Materials & methods


A prospective, observational study was conducted in the patients with CSOM attending ENT outpatient department from November 2014 to November 2015. All the data regarding patient’s demographics and details of antimicrobial agents were recorded in a predesigned study proforma. The data thus obtained wasanalyzed using descriptive statistics.


Results


Out of 500 patients, the majority of the patients belonged to 21-30 years and had a male preponderance. Oral antibiotics were prescribed to 90.8 % of patients and the remaining 9.2% patients were given ototopical antimicrobials. Most common antimicrobials being Fluoroquinolones (64%) followed by Beta lactams (36%). Other concomitant drugs like analgesics, antihistamines, decongestants anti-ulcer agents and multivitamins were prescribed.


Conclusion


The study showed that the most common antimicrobial agents prescribed was fluoroquinolone group as they have antipseudomonal activity and lack ototoxicity. Beta lactams were preferred drugs over fluoroquinolones in children as the latter is associated with tendinitis and cartilage damage.

Keywords

CSOM Antimicrobial agents Oral antimicrobials Ototopical antimicrobials

Article Details

How to Cite
Divya R, Shukrath C, Kavitha Rajarathna, & Puttamadaiah G M. (2021). Prescribing pattern of antimicrobial agents in patients with chronic suppurative otitis media at a tertiary care hospital. International Journal of Research in Pharmacology & Pharmacotherapeutics, 6(3), 312-318. https://doi.org/10.61096/ijrpp.v6.iss3.2017.312-318
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References

  1. [1]. Acuin J Chronic suppurative otitis media - Burden of Illness and Management Options. zeneva: World Health Organization 2004.
  2. [2]. Goycoolea MV, Hueb MM, Ruah C. Definitions and terminology. OtolaryngolClin North America, 24(4), 1991, 757-761.
  3. [3]. Monasta L, Ronfani L, Marchetti F, Montico M, VecchiBrumatti L, Bavcar A et al., Burden of disease caused by otitis media: systematic review and global estimates. PLoS One 7, 2012, 36226.
  4. [4]. Dhingra PL. Chronic suppurative otitis media. In: Diseases of ear, nose and throat. 6, 2014, 68-74
  5. [5]. Sattar A, Alamgir A, Hussain Z, Sarfraz S, Nasir J, Badar-e-Alam. Bacterial spectrum and their sensitivity pattern in patients of chronic suppurative otitis media. J Coll Physicians Surg Pak 22, 2012, 128–129.
  6. [6]. Altuntas A, Aslam A, Eren A. Susceptibility of microorganisms isolated from CSOM to Ciprofloxacin. Eur Arch Otorhino Laryngology 3, 1996, 64 -6.
  7. [7]. Basak B, Gayen GC, Das M, Dhar G, Ray R, Das Ak. Demographic profile of CSOM in a rural tertiary care hospital. IOSR-JOP 4(6), 2014, 43-46.
  8. [8]. Sabella C. Management of otorrhea in infants and children. Paed infectious dis J 12(1), 2000, 1007-8.
  9. [9]. Kumar R, Srivastava P, Sharma M, Rishi S, Nirwan PS, Hemwani K et al., Isolation and antimicrobial sensitivity profile of bacterial agents in chronic suppurative otitis media patients at NIMS hospital, jaipur. IJPBS 3(4), 2013, 265-269
  10. [10]. RenukanandaGS, Santosh UP, George NM. Topical vs Combination Ciprofloxacin in the Management of Discharging Chronic Suppurative Otitis Media. J ClinDiagn Res 8(6), 2014, KC01-KC04.
  11. [11]. Agrawal A, Kumar D, Goyal A, Goyal S, Singh N, Khandelwal G. Microbiological profile and their antimicrobial sensitivity pattern in patients of otitis media with ear discharge. Indian J 19, 2013, 5-8.
  12. [12]. Ghosh A, Rana A, Prasad S. Risk Factors and Microbiology of Chronic Suppurative Otitis Media and its Clinical Significance in a Tartiary Care Setup in Western Uttar Pradesh, India. IJCMAAS 6(3), 2015, 177-183.
  13. [13]. Abubakar K, Abdulkadir R, Abubakar MR, Ugwah-Oguejiofor JC, Abubakar SB. Pattern of Drug Utilization in the Treatment of Chronic Suppurative Otitis Media in a Tertiary Health Institution in Kaduna, Nigeria. J Health Sci 4(1), 2014, 7-10.
  14. [14]. Hirapure PV, Pote MK. Microbial Profile and Antibiograms of Active Patients of Chronic Suppurative Otitis Media in Latur, Maharashtra, India. Int Res J Medical Sci 2(5), 2014, 6-9.
  15. [15]. Sulabh B, Tarun O, Suresh K, Amit S, Pratibha V. Changing microbiological trends in cases of chronic suppurative otitis media patients. Int J Cur Res Rev 05(15), 2013, 76-81.
  16. [16]. Goud SKT, Kumar R, Patil VG, Bhusal A, Rajlakshmi KH, Senpaty S et al., Incidence & Drug Use in Chronic Suppurative Otitis Media (Csom) In Opd E.N.T at Teritary Care Teaching Hospital. IOSR-JDMS 13(4), 2014, 13-19.
  17. [17]. Kardar AA, Usman M, Tirmizi S. Topical quinolone versus topical aminoglycosides in the medical management of chronic suppurative otitis media; A comparative trial. J Surg Pak 8(4), 2003, 6-9.
  18. [18]. Sanjana RK, Singh Y, Reddy NS. Aerobic bacteriology of Chronic Suppurative Otitis Media (CSOM) in a tertiary care hospital: A retrospective study. Journal of College of Medical Sciences 7(2), 2011, 1-8.