Main Article Content

Abstract

Background


Drug utilization studies are necessary to monitor the prescriptions and promote rational drug prescribing among clinicians. Orthopedics department use a wide range of drugs from varied classes to meet the needs of their patients. This tends to result in drug interactions, adverse drug effects and prescription errors leading to increase in hospital cost and decrease in therapeutic compliance of the patients.


Aim


The present study was conducted to analyze the prescribing trends in the Department of Orthopedics of Dr. B R Ambedkar Medical College, Bengaluru.


Methods


A cross sectional prospective observational study was conducted over a period of three months. The prescriptions of patients attending orthopedics departments from both OPD and IPD were collected and analyzed.


Results


A total of 703 prescriptions having 2288 drugs were analyzed with number of drugs per prescription varying from 1 to 5 with average of 3.25. The commonest diagnosis in patients attending the orthopedics department was fractures (38%) followed by lumbago (30%), osteoarthritis (19%), dislocations (6%), bursitis (3%), and synovitis and neuropathies with 1% each.NSAIDS (49%) were the most commonly prescribed drugs followed by antiulcerants (16%), antimicrobials (13%), opioid analgesics (12%), nutraceuticals like calcium and vitamin D3 supplements (4.8%), skeletal muscle relaxants (3.3%), followed by anti inflammatory enzymes and drugs for neuropathy at 1% each. 8% of drugs were prescribed by generics  and 35% of prescriptions had Fixed dose combination (FDC). 69% of drugs were from the National List of Essential Medicines (NLEM) India with approximately 20% of the formulations being injections.


Conclusion


Lacunas like less numbers of prescriptions by generic drugs, polypharmacy and incomplete prescriptions were noted. Thus regular sensitization programmes regarding rational prescribing, and use of generics will help in promotion of rational prescribing among clinicians.

Keywords

Prescription trends Orthopedics NSAIDS Antimicrobials

Article Details

How to Cite
AbishekSrihari, Dr.Shanmukananda P, & Dr.Purushotham K. (2021). Prescribing trends in the department of orthopedics of a tertiary care teaching hospital. International Journal of Research in Pharmacology & Pharmacotherapeutics, 6(3), 297-301. https://doi.org/10.61096/ijrpp.v6.iss3.2017.297-301

References

  1. [1]. Wade O. Drug utilization studies - the first attempts. Plenary lecture. In: Sjöqvist F, Agenäs. Drug utilization studies: implications for medical care. ActaMedicaScandinavica, 1, 1984, 683:7-9.
  2. [2]. Dukes MNG. Development from Crooks to the nineties. In: Auditing Drug Therapy. Approaches towards rationality at reasonable costs. Stockholm, Swedish Pharmaceutical Press, 1992.
  3. [3]. Consumption of drugs. Report on a symposium in Oslo 1969. Copenhagen, WHO Regional Office for Europe, 1970 (EURO 3102).
  4. [4]. Laporte J. R. Towards a healthy use of Pharmaceuticals. Development dialogue. 2, 1985, 48-55
  5. [5]. WHO. How to investigate drug use in health facilities: selected drug use indicators, Geneva, World Health Organization, 1993, WHO/DAP/93 1, 1993, 1-87.
  6. [6]. Shankar PR, Pai R, Dubey AK, Upadhyay DK. Prescribing patterns in the orthopaedics outpatient department in a teaching hospital in Pokhara, Western Nepal. Kathmandu Univ Med J (KUMJ). 5(1), 2007, 16-21.
  7. [7]. Banerjee I, Bhadury T, Agarwal M. Prescribing pattern in orthopedics outpatient department of a medical college in India. Int J Basic ClinPharmacol4, 2015, 1175-1177
  8. [8]. Shaikh U, Chandra SN, Jayasree T, Shankar J, Kotipalli R. Prescription Trends in department of Orthopaedics at Tertiary Care Teaching Hospital. Journal of Chemical and Pharmaceutical Research, 5(11), 2013, 512-517.
  9. [9]. Muraraiah S, Rajarathna K, Vishwanath M, Ramaswamy A, Kamath S, Seshu S, et al.. Evaluation of WHO prescribing indicators among orthopaedic inpatients at a tertiary care hospital. J Chem Pharm Res. 6(8), 2014, 278–80.
  10. [10]. "Generic Drugs", Center for Drug Evaluation and Research, U.S. Food and Drug Administration www.medterms.com: definition of generic drug
  11. [11]. Wadagbalkar P, Nagla A, Raipurkar S, Patel P. Prescription pattern study of drugs in Orthopedics Outpatient department (OPD) of a Rural Medical College Hospital & Research centre in MP. Indian Journal of Orthopaedics Surgery 2(4), 2016, 367-371
  12. [12]. Srividya BP, Shashikumar NS, Amardeep G. Retrospective audit of prescription of drugs among inpatients of orthopedic wards at Medical College Teaching Hospital, Mandya. Natl J Physiol Pharm Pharmacol 6, 2016, 282–285.
  13. [13]. WHO guidelines for generic drugs. The Impact of Implementation of ICH Guidelines in Non-ICH Countries - Regulatory Support Series No. 009; (2002; 34 pages)