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Abstract

Iodine is a trace element naturally present in some foods and sea-food and available as an important nutrient and dietary supplement. Iodine deficiency is a global health issue and has multiple adverse effects on growth and development, and is the most common cause of preventable mental retardation in the world. Chronic, severe iodine deficiency in utero causes cretinism, a condition characterized by mental retardation,  mutism, motor spasticity, stunted growth, delayed sexual maturation and other physical and neurological abnormalities and is also reported to be linked with Autism, cysts, certain Cancers along with hypo and hyper thyroidism, goiter etc. Various campaigns and awareness programs have been conducted to fight the Iodine deficiency. The Salt iodization programme in India dates back to late 50’s by Ramalingaswami and his team established Iodine deficiency as the causative factor for endemic goiter and consuming salt iodized with potassium iodate as the most economic and easiest means of its prevention and control in a population. This study encouraged by the Govt. of India also helped to launch National Goiter Control Programme (NGCP). A revolutionary BINDI is a simple patch or a DOT comprising of Iodine solution in adequate quantities that works to fight against and deliver the iodine at constant and controlled rate by subdermal route throughout the month. The bindi need to be worn everyday for up to eight hours to be effective and even by the pregnant women. It contains a solution of 150-200 µg of Iodine coated on the nicotine like patch. Ground-breaking technology of life saving DOT of Bindi might work in the safe and controlled delivery of Iodine for various Iodine deficiency disorders by reducing the problems of thyroid intake and improving patients’ compliance.

Keywords

Iodine Bindi Thyroid disorders Mutism Subdermal salt iodization programme

Article Details

How to Cite
Keerthi G, & Raja K. Rajeswari. (2021). Fight the iodine deficiency: advances in the iodine supplement as life savingdot-- a critical review . International Journal of Research in Pharmacology & Pharmacotherapeutics, 6(3), 289-296. https://doi.org/10.61096/ijrpp.v6.iss3.2017.289-296

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