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Submitted
Apr 30, 2021
Published
Apr 30, 2021
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Abstract

Background


Wounds are the common skin disorders. It can occur by various methods. Agents having wound healing activity have wide therapeutic uses. The present study was planned to evaluate wound healing activity of hydroalcoholic extract of Vetiveria ziznoides roots in Wistar Albino rats


Materials and Methods


This study was done in the department of Pharmacology, SMIMS. Total 24 rats were divided in to four groups each of 6 rats. G-I: Control, G-II: HAEV.Zroot (75 mg/kg), G-III: HAEV.Zroot (150 mg/kg) and G-IV: HAEV.Zroot (300 mg/kg). 6 cm length of incision was made at para vertebral palace. Rats were given test drugs one week before incision made and one week after incision. Control group treated with distilled water. On 15th day tensile strength was measured.


Results


Significant difference was observed in the tensile strength with high dose of test drug compared to low dose and control group.


Conclusion


In conclusion, pre-administration of V.Z root increased wound healing compared to control group. Further studies required to find the mechanism of action.

Keywords

Anti-oxidant Hydroalcoholic extract Healing Incision Para vertebral Tensile strength

Article Details

How to Cite
Chakradhar T, & Sarath Babu K. (2021). Evaluation of wound healing activity of hydroalcoholic extract of vetiveria ziznoides roots in wistar albino rats. International Journal of Research in Pharmacology & Pharmacotherapeutics, 7(1), 97-99. https://doi.org/10.61096/ijrpp.v7.iss1.2018.97-99
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