Main Article Content

Abstract

The prevalence of diabetes is increasing globally. Women with Gestational Diabetes Mellitus are an ideal group for the primary prevention of diabetes as they are at increased risk of future diabetes, predominantly type 2 diabetes, as are their children. A prospective observational study was carried out in gynaecology department over a period of 6 months enrolling 150 patients. The study was carried out to identify the prevalence of GDM, to assess the prescribing pattern of anti-diabetic drugs in GDM, to identify the risk factors involved, to assess the patient’s level of knowledge about diabetes and to provide patient counselling. 106 patients were diagnosed with GDM. Most commonly prescribed anti-diabetic drugs were metformin followed by insulin. The risk factors identified were age above 30 years, obesity, family history and prediabetes. The occurrence of maternal and neonatal complications in the GDM patients were observed and most frequent complication found was caesarean in 49 cases.  The assessment of distribution of patients based on gestation period revealed that patients at gestational age of 24-26 weeks of pregnancy were more frequently diagnosed with GDM. A standard questionnaire was used to assess the level of knowledge about diabetes in GDM patients. Based on the level of knowledge, the patients were educated regarding the disease and lifestyle modification with the help of patient information leaflet. . The severity of drug interactions were evaluated and found that 13 prescriptions had major interactions, followed by 36 moderate interactions and 12 minor interactions. The present study points out the role of a clinical pharmacist in improving the patient care and overall quality of life in GDM patients.

Keywords

Gestational Diabetes Mellitus Prediabetes Gestation period Quality of life

Article Details

How to Cite
Chitra B, Shreedarshan M, Tharayil Nishi Nainan, & Vishnu N. (2021). Study on the prevalence of gestational diabetes mellitus at a tertiary care hospital. International Journal of Research in Pharmacology & Pharmacotherapeutics, 7(1), 7-11. Retrieved from https://ijrpp.com/ijrpp/article/view/227

References

  1. [1]. Nalinee Poolsup, Naeti Suksomboon, Muhammad Amin: Efficacy and Safety of Oral Antidiabetic Drugs in Comparison to Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis. Plos One 9(10), 2014, 1-13.
  2. [2]. Zahid Hussain, Zuraidah Mohd Yusoff, Syed Azhar Syed Sulaiman: Evaluation of knowledge regarding gestational diabetes mellitus and its association with glycaemic level. Archives of Pharmacy Practice 5(2), 2014, 84-90.
  3. [3]. Malik Waseem Raja, Tufeel Ahad Baba, Asif Jeelani Hanga, Safoora Bilquees : A study to estimate the prevalence of gestational diabetes mellitus in an urban block of kashmir valley (north india). International Journal of Medical Science and Public Health 3(2), 2014, 91-195.
  4. [4]. X. Xiong, L.D. Saunders, F.L. Wang, N.N. Demianczuk. Gestational diabetes mellitus: prevalence, risk factors, maternal and infant outcomes. International Journal of Gynecology & Obstetrics 75, 2001, 221-228.
  5. [5]. Andrea Huidobro, Andrew Prentice, Tony Fulford, Carmen Parodi, Jaime Rozowski: Gestational diabetes, comparison of women diagnosed in second and third trimester of pregnancy with non GDM women: Analysis of a cohort study. Rev Med Chile 138, 2010, 316-321.
  6. [6]. Prema Prabhudev, Shridevi A. S., Madhusoodana R. Bhovi: A clinical study of prevalence of gestational diabetes mellitus and associated risk factors at a tertiary care centre in Karnataka, India. Int J Reprod Contracept Obstet Gynecol. 4(6), 2015, 1840 -1845.
  7. [7]. Jiwani A, Marseille E, Lohse N, Damm P, Hod M, Kahn JG: Gestational diabetes mellitus: results from a survey of country prevalence and practices. J Matern Fetal Neonatal Med. 25(6), 2012, 600 - 10.
  8. [8]. Jovanovic L, Savas H, Mehta M, Trujillo A, Pettitt DJ: Frequent monitoring of A1C during pregnancy as a treatment tool to guide therapy. Diabetes Care. 34(1), 2011, 53- 4.
  9. [9]. Wilson N, Ashawesh K, Kulambil Padinjakara RN, Anwar A: The multidisciplinary diabetes-endocrinology clinic and postprandial blood glucose monitoring in the management of gestational diabetes: impact on maternal and neonatal outcomes. Exp Clin Endocrinol Diabetes. 117(9), 2009, 486 - 9.
  10. [10]. Li-Ping Zhao, Xiao-Yan Sheng, Shuang Zhou, Ting Yang: Metformin versus insulin for gestational diabetes mellitus: a meta-analysis. British Journal of Clinical Pharmacology. 80(5), 2015, 1224 - 1234.