Main Article Content

Abstract

Ichnocarpus frutescens has a broad spectrum in the indigenous system of medicine. It is commonly known as the black creeper belonging to the family of apocynaceae. The present study investigates the physicochemical and phytochemical characteristics of three different extracts of leaves of Ichnocarpus frutescens by using standard methods. The phytochemical evaluation included colour and consistency, fluorescent behaviour and qualitative analysis. The Physicochemical screening determined extractive value, ash value and moisture content. Results revealed the presence of carbohydrates, glycosides, flavonoids, phytosterols and phenolic compounds. This study of Ichnocarpus frutescens will help in quality analysis of crude drug and lay down the standards which can be useful in future experimental studies.

Keywords

Ichnocarpus frutescens phytochemical physicochemical

Article Details

How to Cite
Suchitra Naidu T, Emmanuel S, Aishwarya, & Durga M. (2021). Studies on physicochemical and phytochemical screening of different extracts of Ichnocarpus frutescens. International Journal of Research in Pharmacology & Pharmacotherapeutics, 4(2), 140-146. https://doi.org/10.61096/ijrpp.v4.iss2.2015.140-146

References

  1. [1] Sony Himesh, Sharma Sarvesh, Patel Sita Sharan, Mishra K. Preliminary Phytochemical Screening And HPLC Analysis Of Flavonoid from Methanolic Extract Of Leaves Of Annona Squamosa.International Research Journal Of Pharmacy 2011;5: 242-246.
  2. [2] Chatterjee A. and Pakrashi S. (2003) ‘The Treatise of Indian Medicinal Plants’, NISCAIR, New Delhi, Vol. 4, pp. 110-112.
  3. [3] Pandurangan A, Khosa RL, Hemalatha S. Anti-inflammatory & Analgesic Activities of Roots of Ichnocarpus frutescens. Pharmacologyonline 2008; I: 392-399.
  4. [4] Kumarappan C, Mandal SC. α-Glucosidase inhibitory activity and in-vitro antioxidant activities of alcohol–water extract of Ichnocarpus frutescens leaves. Medicinal Chemistry Research 2008; 17: 219-233.
  5. [5] Barik R, Jain S, Qwatra D, Joshi A, Tripathy G, Sharan GR. Antidiabetic activity of Ichnocarpus frutescens in Streptozotocin –nicotinamide induced type-II diabetes in rats. Indian Journal of Pharmacology 2008; 40 (1): 19-22.
  6. [6] Dash DK, Nayak SS, Samanta S. Antitumor activity and antioxidant role of Ichnocarpus frutescens against Ehrlich ascites carcinoma in swiss albino mice. Natural Product Science 2007; V 13(1): 54-60.
  7. [7] Khandelwal KR. Practical pharmacognosy, Nirali Publications Pune, 1995; 1: 140- 143.
  8. [8] World Health Organization. Quality control methods for medicinal plant materials. Geneva 1998; 28-29.
  9. [9] Anonymous, WHO guidelines, 1st Edition, AITBS Publishers and Distributors: NewDelhi. 2002; pp28, 30, 41, 46.
  10. [10] Rosenthaler L. The chemical investigations of plants, G. Bellsand Son Ltd, London 1930; 23, 27, 119, 155.
  11. [11] Finar IJ. Organic Chemistry, The english language book society and longmann green Co. Ltd. London 1973; 5: 342, 363, 656.
  12. [12] Sim SK. Medicinal plant glycosides, University of Toronto Press. 1968; 2: 25.
  13. [13] Peach K, Tracy MV. Modern methods of plant analysis, Springer Verlag, Berlin 1955; 1 (4): 367- 374.
  14. [14] Harbourne JB. Phytochemical analysis, Chapman and Hall company Ltd, London 1973; 1: 5-6.
  15. [15] Kar Ashutosh. Pharmacognosy and Pharmabiotechnology. New age publishers & distributors New Delhi.2004; 2: 147.
  16. [16] Trease GE, Evans WC. Pharmacognosy Balliere Tindall Press, London 1983; 56- 57.
  17. [17] Kokate CK, Purohit AP, Gokhale SB, Practical pharmacognosy, Nirali Prakashan, Pune, 1994; 2: 54-60.
  18. [18] Wallis TE. Textbook of pharmacognosy, CBS Publishers & Distributors, New Delhi 1985; 5: 56- 57.
  19. [19] P.Varadarajan G, Rathinaswamy, and Asirvatahm D Antimicrobial properties and phytochemical constituents of Rheo discolor. Ethnobotanical Leaflet.2008; 12: 841–845.
  20. [20] P. Tiwari, B. Kumar, M. Kaur, G. Kaur, H. Kaur, Int. Pharm. Sciencia, 2011, 1, 98-106 .
  21. [21] Singh, R., Singh, S.K., Arora, S. 2007. Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn. Fod Chem. Toxicol., 45: 1216-1223.
  22. [22] Han, X., Shen, T., Lou, H. 2007. Dietry polyphenols and their biological significance. Int. J. Mol. Sci., : 950-988.
  23. [23] Brown, J.E., Rice-Evans, C.A. 1998. Luteolin rich artichoke extract protects low density lipoprotein from oxidation in vitro. Free Radical Res., 29: 247-255.
  24. [24] Krings, U., Berger, R.G. 2001. Antioxidant activity of roasted foods. Food Chem., 72: 223-229.
  25. [25] Ali, S.S., Kasoju, N., Luthra, A., Singh, A., Sharanabasava, H., Sahuand, A., Bora, U. 2008. Indian medicinal herbs as source of antioxidants. Food Res. Int., 41: 1-15.
  26. [26] Okwu, D.E. 2004. Phytochemicals and vitamin content of indigenous species of southeastern Nigeria. J.Sustain. Agric. Environ., 6(1): 30-37.
  27. [27] Just, M.J., Recio, M.C., Giner, R.M., Cueller, M.U., Manez, S., Billia, A.R., Rios, J.L. 1998. Antiinflammatory activity of unusual lupine saponins from Bupleurum fruticescens, 64: 404-407.
  28. [28] Sodipo, O.A., Akiniyi, J.A., Ogunbamosu, J.U. 2000. Studies on certain on certain characteristics of extracts of bark of Pansinystalia macruceras (K schemp) picrre Exbeille. Global J. Pure Appl. Sci., 6: 83-87.
  29. [29] Raquel, F.E. 2007. Bacterial lipid composition and antimicrobial efficacy of cationic steroid coppounds. Biochemica et Biophysica Acta. 2500-2509.
  30. [30] Okwu, D.E. 2001. Evaluation of chemical composition of medicinal plants belonging to Euphorbiaceae. Pak Vet. J., 14: 160-162.
  31. [31] Nobori, T., Miurak, K., Wu, D.J., Takabayashik, L.A, Carson, D.A. 1994. Deletion of cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature, 46: 753-756.
  32. [32] Antherden, L.M. 1969. Textbook Of Pharmaceutical Chemistry, 8th edn., Oxford University Press, London , pp. 813-814.
  33. [33] Harborne, J.B. 1973. Phytochemicals Methods. Chapman and Hall Ltd., London, pp. 49-188.
  34. [34] Stray, F. 1998. The Natural Guide to Medicinal herbs And Plants. Tiger Books International, London , pp. 12-16.
  35. [35] Okwu, D.E., Okwu, M.E. 2004. Chemical composition of Spondias mombin linn. plant parts. J. Sustain. Agric. Environ ., 6(2): 140-147.
  36. [36] Nyarko, A.A., Addy, M.E. 1990. Effects of aqueous extract of Adenia cissampeloides on blood pressure and serum analyte of hypertensive patients. Phytotherapy Res ., 4(1): 25-28.