Main Article Content

Abstract

In the present investigation preliminary phytochemical screening on leaves extract of Basella alba revealed the presence of Proteins, fat, carbohydrates, fiber, ash, calcium, vitamins, thiamine, riboflavin, niacin. The antipyretic activity of ethanolic and aqueous extract of leaves of Basella alba was evaluated in albino rats. The ethanolic and aqueous extracts showed significant activity against yeast induced pyrexia at 200 mg/kg and 400 mg/kg respectively. The antipyretic effects of the extracts were comparable to that of standard drug (Paracetamol 150 mg/kg).

Keywords

Basella alba Phytochemistry Anti-pyretic activity

Article Details

How to Cite
R. Chandrasekar, B. Sivagami, & S. Mounika Reddy. (2021). Study of antipyretic activity of Basella alba leaf extract. International Journal of Research in Pharmacology & Pharmacotherapeutics, 4(1), 45-48. https://doi.org/10.61096/ijrpp.v4.iss1.2015.45-48

References

  1. [1] Roshan Adhikari, Naveen Kumar HN, Shruthi SD. A Review on Medicinal Importance of Basella alba L.International Journal of Pharmaceutical Sciences and Drug Research 2012; 4(2): 110-114
  2. [2] Grubben GJH, Denton OA. Plant Resources of tropical African vegetables. Wageningen; Backhuys Leiden (CTA) Wageningen: PROTA Fundation; 2004.
  3. [3] Kumar P. INDIAN SPINACH, Basella alba (PUI) succulent, Branched, smooth, twining herbaceous vine. Best Nutrition, 2010
  4. [4] Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hassain MI, Fuchs GJ, Brown KH. Daily consumption of Indian spinach (B. alba) or sweet potatoes has positive effect on total-body vitamin A store in Bangladeshi men. Am J ClinNutr. 2004; 80(3): 705-714.
  5. [5] Chou CT. The anti-inflammatory effect of Tripterygiumwilfordii Hook F on adjuvant-induced paw edema in rats and inflammatory mediators release. Phytother Res. 1997; 11:152-154.
  6. [6] Harborne JB. A Guide to modern techniques of plant analysis. Edn 2, Kluwar academic publishers, USA, 1998, 85.
  7. [7] Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy.Edn 39,Nirali Prakashan, Pune,2007, PP.108-109.
  8. [8] Subrata k Mandal, Subhash C Mandal, AK Das, Hui Tag and Tapas Sur. Antipyretic activity of eupatorium adenophorum leaf extract. Indian J Nat Prod. 21(1), 6-9.
  9. [9] Vikas V Patil, Bhangale SC, Narkhede SB, Jawle NM, Patil VR. Analgesic and Antipyretic activities of Ficus Bengalensis Bark. International Journal of Pharmaceutical Research, 2010, 2(2), 16-20.
  10. [10] Gupta Mradu, Banerjee Dalia, Mukherjee Arup, Studies of Anti-inflammatory, Anti-pyretic and Analgesic effects of aqueous extract of traditional herbal drug on rodents. Int Res J Pharm. 2013.