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Apr 16, 2021
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Apr 16, 2021
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Abstract

The present research was carried out to evaluate Antidiabetic activity of Heliotropium indicum ethanolic extract in alloxan and streptozotocin induced diabetic rats Helitropium indicum whole plant was extracted using ethanol as solvent by Soxhlet apparatus. The extract was subjected to preliminary phytochemical screening. Acute oral toxicity studies were performed to determine test dose. Alloxan and streptozotocin were used for inducing diabetes in albino Wistar rats. Preliminary phytochemical screening revealed the presence of alkaloids, carbohydrates, glycosides, saponins, tannins flavonoids, proteins, and amino acids. Doses up to 2000mg/kg were found to be safe after acute toxicity tests. The results suggested that EHI possess anti diabetic activity against diabetes induced by both alloxan and streptozotocin.

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Heliotropium indicum ethanolic extract alloxan and streptozotocin

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Syed Safiullah Ghori, Nafeesunnisa Begum, & Mohammed Shoibuddin Khateeb. (2021). Antidiabetic activity of ethanolic extract of Heliotropium indicum whole plant against alloxan and streptozotocin induced diabetis in rats. International Journal of Research in Pharmacology & Pharmacotherapeutics, 4(1), 24-36. https://doi.org/10.61096/ijrpp.v4.iss1.2015.24-36
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