Lacto-D3; The sunshine Vitamin provides Vitamin D3 optimum Strength

Abstract

Supplementation of cholecalciferol (vitaminD₃) significantly reduces all-cause mortality emphasizes the medical, ethical, and legal implications of promptly diagnosing and adequately treating VitamnD3 deficiency. Not only are such deficiencies common, and probably the rule, VitamnD₃ deficiency is implicated in most of the diseases of civilization.  Vitamin D3’s final metabolic product is a potent, pleiotropic, repair and maintenance, seco-steroid hormone that targets more than 200 human genes in a wide variety of tissues, meaning it has as many mechanisms of action as genes it targets. One of the most important genes VitamnD₃ up-regulates is for cathelicidin, a naturally occurring broad-spectrum antibiotic. Natural VitamnD₃ levels, those found in humans living in a sun-rich environment, are between 40-70 ng/mL, levels obtained by few modern humans. Assessing serum 25-hydroxy-VitamnD₃ (25(OH)D) is  the only way to make the diagnosis and to assure treatment  is adequate and safe. Three treatment modalities exist for VitaminD3 deficiency: sunlight, artificial ultraviolet B (UVB) radiation, and VitamnD₃ supplementation. Treatment of vitamin D deficiency in otherwise healthy patients with 2,000-7,000 IU VitamnD₃ per day should be sufficient to maintain year-round 25(OH)D levels between 40-70 ng/mL. In those with serious illnesses associated with VitamnD3 deficiency, such as cancer, heart disease, multiple sclerosis, diabetes, autism, and a host of other illnesses, doses should be sufficient to maintain year-round 25(OH)D levels between 55-70 ng/ mL. Vitamin D 3-deficient patients with serious illness should not only be supplemented more aggressively than the well, they should have more frequent monitoring of serum 25(OH) D and serum calcium. Vitamin D3 should always be adjuvant treatment in patients with serious illnesses and never replace standard treatment. Theoretically, pharmacological doses  of VitamnD₃ (2,000 IU/kg/day for three days) may produce  enough of the naturally occurring antibiotic cathelicidin to cure  common viral respiratory infections, such as influenza and  the common cold, but such a theory awaits further science. The present paper Reviews the role of VitamnD₃ in preventing different human disorders.