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Abstract

Ethanol extracts of Ficus carica L. fruits were tested for diuretic activity in rats. The parameters studied on individual rat were total urine volume, urine concentration of Na+, K- and Cl-. In the present study ethanol extracts of Ficus carica, L. (100 and 200mg/kg of body weight) showed an increase in urine volume, cation and anion excretion. Furosemide was used as the reference diuretic. Based on the above results, we can conclude that Ficus carica L. treatment produced a marked diuresis when rats were acutely treated. In our study, no lethality was observed at least for the dose (2000mg/kg body weight), and duration used. The best results of urine output observed with the ethanolic extract of Ficus carica L. fruits obtained through this evaluation. These findings support the traditional uses of Ficus carica L. as diuretic agents.

Keywords

Ficus carica L diuretic activity Lipschitz test

Article Details

How to Cite
Sruthi.B, Sunny.G, Hajra Naz, & S.Sakthivel. (2021). DIURETIC ACTIVITY OF ETHANOLIC EXTRACTS OF FICUS CARICA L. FRUITS . International Journal of Research in Pharmacology & Pharmacotherapeutics, 1(1), 23-26. https://doi.org/10.61096/ijrpp.v1.iss1.2012.23-26