Main Article Content
Abstract
Background
One of global problem encountered nowadays is adverse drug reaction, which affect the majority of population both the children and adults. Adverse drug reactions (ADRs) are the consequences of drug therapy, and it is fourth leading cause of morbidity and mortality in world. Pharmacovigilence plays an important role in the reduction of ADRs. Voluntary reporting of ADRs by health care professional is an important tool in the success of pharmacovigilence programme. So this study was conducted to assess the awareness of pharmacovigilence and to evaluate the knowledge, attitude and practices among doctors in tertiary care teaching hospital in Bastar region of Chhattisgarh in India.
Methods
A cross-sectional questionnaires based study was carried out among doctors of tertiary care teaching hospital with Govt. Medical College Jagdalpur. 85 doctors (physician) Were enrolled in our study. A Prevalidated 21 questionnaires of knowledge, attitude and practice towards Pharmacovigilance were developed and after taking inform consent, questionnaires were directly distributed to the physician, 7-8 days time was given to fill the form. The filled KAP questionnaires were analyzed question wise and their percentage value was calculated by Microsoft excel and graph pad prism version 6.01.
Result
In our study 120 questionnaires were distributed to healthcare professional of tertiary care teaching hospital of which 85(70.8%) responded , in which 45 consultant were from different clinical department and 40 intern were filled form and sent it back .ADRs reporting was considered very important by almost all of them ,but actual practice was lacking as only 10.5 % had reported any ADR .
Conclusion
The healthcare professional were aware of the importance of ADR reporting, but lack of knowledge about the procedure where to report ,whom to report ,unavailability of ADR reporting form, uncertain association are the most common cause of underreporting. So there is need to conduct an awareness programme about the pharmacovigilence as it is tertiary care center for patients safety.
Keywords
Article Details
References
- [1]. Medhi B, Prakash A .Tools for patient safety; pharmacovigilence, biovigillance. A textbook of Advanced pharmacology 1, 2018, 491-505.
- [2]. Lazarou J, Pomeranz BH, Corey PN. Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies. JAMA. 279(15), 1998, 1200-5.
- [3]. S.Ganesan, G. Vikneswaran, KC Reddy, DK Subrahmanyam, Ch. Adithanet alA Survey on Knowledge, Attitude and Practice of Pharmacovigilance towards Adverse drug reactions reporting among Doctors and Nurses in a Tertiary Care Hospital in South India .J Young Pharma, 8(4), 2016, 471-476
- [4]. Pharmacovigilance world health organization 2015 www.who.int accessed on 19
- [5]. Pharmacovigilence programme of india https://ipc.gov.in//PvPI/about.cited on 19
- [6]. Ratan JL, Mangala L. An update on the Pharmacovigilance Programme of India. Front Pharmacol.6, 2015, 194. 201
- [7]. Saha K,Rath B ,Agrawal R .A survey of knowledge attitude and practice of adverse drug reaction monitoring among doctors in western odisha region .Int J Basic Clin Pharmacology7(11), 2018, 2234-2239
- [8]. Dhananjay K ,Himasri . E .et al. A study of assessing the knowledge, attitude, practice of pharmacovigilence among the medical students of south Indian teaching hospital. Int J Basic Clin Pharmacol. 6(1), 2017, 43-47
- [9]. De Langen J,van Hunsel F,Passier A, de Jong –van den Berg L, van Grootheest K.Adverse drug reaction reporting by patients in the Netherlands three years of experience .Drug safety. 31(6), 2008, 515-24
- [10]. Oshikoya KA, Awobusuyi JO. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol 14, 2009, 9
- [11]. B.vora.M, Barvalia M et al : A survey of the knowledge, attitude and practice towards the pharmacovigilence and adverse drug reaction in healthcare professional of tertiary care teaching hospital ,Bhavnager India IJPSR 11(5), 2014, 820-826
- [12]. Cosentino M ,Leoni O ,Banfi F ,Lecchini S ,Frigo G .Attitude to Adverse drug reaction reporting by medical practitioner in a Northern Italian district ,Pharmacological research . 35(2), 1997, 85-8.
- [13]. Eland IA, Belton KJ, van Grootheest AC, Meiners AP, Rawlins MD, Stricker BH. Attitudinal survey of voluntary reporting of adverse drug reactions. Br J Clin Pharmacol 48, 1999, 623-7.
- [14]. Radhakrishnan R, Danturulu SV, Varma M. An Educational Intervention to assess Knowledge Attitude Practice of pharmacovigilance among Health care professionals in an Indian tertiary care teaching hospital Int J of Pharm Tech Research. 3(2), 2011, 678-92.
- [15]. Meher BR, Joshua N ,Asha B,Mukherji D .A questionnaire based study to asses knowledge ,attitude and practice of pharmacovigilance among undergraduates medical students in atertiary care teaching hospital of south India .perspect clin Res 6, 2015, 217-21.
- [16]. Hazell L, Shakir SA .underreporting of adverse drug reaction: a systemic review .drug safty 29(5), 2006, 385 -96.
- [17]. Figueiras A, Herdeiro MT, Polonia J, et al. An educational intervention to improve physician reporting of adverse drug reactions: a cluster-randomized controlled trial. JAMA 296(9), 2006, 1086-93. 31.
- [18]. Tabali M, Jeschke E, Bockelbrink A, et al. Educational intervention to improve physician reporting of adverse drug reactions (ADRs) in a primary care setting in complementary and alternative medicine. BMC Public Health 9, 2009, 274.
- [19]. Bracchi RC, Houghton J, Woods FJ, et. al. A distance-learning programme in pharmacovigilance linked to educational credits is associated with improved reporting of suspected adverse drug reactions via the UK yellow card scheme. Br J Clin Pharmacol 60(2), 2005, 221-3.
References
[1]. Medhi B, Prakash A .Tools for patient safety; pharmacovigilence, biovigillance. A textbook of Advanced pharmacology 1, 2018, 491-505.
[2]. Lazarou J, Pomeranz BH, Corey PN. Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies. JAMA. 279(15), 1998, 1200-5.
[3]. S.Ganesan, G. Vikneswaran, KC Reddy, DK Subrahmanyam, Ch. Adithanet alA Survey on Knowledge, Attitude and Practice of Pharmacovigilance towards Adverse drug reactions reporting among Doctors and Nurses in a Tertiary Care Hospital in South India .J Young Pharma, 8(4), 2016, 471-476
[4]. Pharmacovigilance world health organization 2015 www.who.int accessed on 19
[5]. Pharmacovigilence programme of india https://ipc.gov.in//PvPI/about.cited on 19
[6]. Ratan JL, Mangala L. An update on the Pharmacovigilance Programme of India. Front Pharmacol.6, 2015, 194. 201
[7]. Saha K,Rath B ,Agrawal R .A survey of knowledge attitude and practice of adverse drug reaction monitoring among doctors in western odisha region .Int J Basic Clin Pharmacology7(11), 2018, 2234-2239
[8]. Dhananjay K ,Himasri . E .et al. A study of assessing the knowledge, attitude, practice of pharmacovigilence among the medical students of south Indian teaching hospital. Int J Basic Clin Pharmacol. 6(1), 2017, 43-47
[9]. De Langen J,van Hunsel F,Passier A, de Jong –van den Berg L, van Grootheest K.Adverse drug reaction reporting by patients in the Netherlands three years of experience .Drug safety. 31(6), 2008, 515-24
[10]. Oshikoya KA, Awobusuyi JO. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol 14, 2009, 9
[11]. B.vora.M, Barvalia M et al : A survey of the knowledge, attitude and practice towards the pharmacovigilence and adverse drug reaction in healthcare professional of tertiary care teaching hospital ,Bhavnager India IJPSR 11(5), 2014, 820-826
[12]. Cosentino M ,Leoni O ,Banfi F ,Lecchini S ,Frigo G .Attitude to Adverse drug reaction reporting by medical practitioner in a Northern Italian district ,Pharmacological research . 35(2), 1997, 85-8.
[13]. Eland IA, Belton KJ, van Grootheest AC, Meiners AP, Rawlins MD, Stricker BH. Attitudinal survey of voluntary reporting of adverse drug reactions. Br J Clin Pharmacol 48, 1999, 623-7.
[14]. Radhakrishnan R, Danturulu SV, Varma M. An Educational Intervention to assess Knowledge Attitude Practice of pharmacovigilance among Health care professionals in an Indian tertiary care teaching hospital Int J of Pharm Tech Research. 3(2), 2011, 678-92.
[15]. Meher BR, Joshua N ,Asha B,Mukherji D .A questionnaire based study to asses knowledge ,attitude and practice of pharmacovigilance among undergraduates medical students in atertiary care teaching hospital of south India .perspect clin Res 6, 2015, 217-21.
[16]. Hazell L, Shakir SA .underreporting of adverse drug reaction: a systemic review .drug safty 29(5), 2006, 385 -96.
[17]. Figueiras A, Herdeiro MT, Polonia J, et al. An educational intervention to improve physician reporting of adverse drug reactions: a cluster-randomized controlled trial. JAMA 296(9), 2006, 1086-93. 31.
[18]. Tabali M, Jeschke E, Bockelbrink A, et al. Educational intervention to improve physician reporting of adverse drug reactions (ADRs) in a primary care setting in complementary and alternative medicine. BMC Public Health 9, 2009, 274.
[19]. Bracchi RC, Houghton J, Woods FJ, et. al. A distance-learning programme in pharmacovigilance linked to educational credits is associated with improved reporting of suspected adverse drug reactions via the UK yellow card scheme. Br J Clin Pharmacol 60(2), 2005, 221-3.