@article{Sushila_2023, title={In vitro antioxidant activity and total phenolic content of Citrullus colocynthis fruits}, volume={12}, url={https://ijrpp.com/ijrpp/article/view/466}, DOI={10.61096/ijrpp.v12.iss1.2023.42-47}, abstractNote={<p>Generation of free radicals is the cause of oxidative stress related diseases and antioxidants by quenching free radicals have a significant contribution in the prevention of diseases. As synthetic antioxidants are responsible for causing toxicity, mutagenesis and tumour, search for antioxidants of plant origin is becoming more prominent. Present study was carried out to determine total phenolic content, reducing power, metal chelating and free radical (DPPH superoxide and hydroxyl) scavenging activity of fruit extract of <em>Citrullus colocynthis</em>. Total phenolic content was determined using the Folin-ciocalteu reagent and expressed as mg/g gallic acid equivalent. Antioxidant activity was found to be highest in methanolic extract which also possesses highest phenolic content (57.34mg/g). A Positive correlation was observed between total phenolic content and different antioxidant assays thus confirming the role of phenolics in contributing to the antioxidant potential of <em>C. colocynthis</em> fruits&nbsp;</p> <p>&nbsp;</p&gt;}, number={1}, journal={International Journal of Research in Pharmacology & Pharmacotherapeutics}, author={Sushila, Dr. Sushila Saini}, year={2023}, month={Mar.}, pages={42-47} }