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Herbal drugs classification system represent as an important system of medicine for the treatment of a wide array of diseases. The medicinal plants from India provide a diverse source for health care moieties in order to prevent different pathological states. Alpinia officinarum, known as lesser galangal. Alpinia officinarum, a plant from ginger family.The paracetamol 640mg/kg BW P.O induced injuries of liver in animal are mostly used to screen out the hepatoprotective effect of extract. In the present study total phenolic and flavonoid contents, in vitro antioxidant, and in vivo hepatoprotective (on paracetamol induced intoxication in experimental male Sprague Rats) Potentials of the Alpinia officinarum rhizome ethanolic extract were determined. For the identification of possible phytochemical test. Glycoside, Phenol, Tannins, Steroids, Flavonoids were identified Alpinia officinarum extract at dose of 200mg/kg BW P.O and 400 mg/kg BW P.O were given for 14days to paracetamol intoxicated rats and observed results were compared with standard silymarin 50 mg/kg. The level of lever enzymes like aspartate aminotransferase, alanine aminotransferase, alkaline phosphate, total protein and total bilirubin. Furthermore histopathological analysis of the liver tissues of control and treated groups also confirmed hepatoprotective effect of the Alpinia officinarum which was most probably due to its high antioxidant phenolic and flavonoids phytoconstituents.


Alpinia officinarum Hepatoprotective Pharacetamol, Silymarin

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How to Cite
G. Kamal, & V. Suresh. (2024). Hepatoprotective evaluvation of galanga (alpinia officinarum) rhizome extract against paracetamol induced hepatotoxicity in rats. International Journal of Research in Pharmacology & Pharmacotherapeutics, 13(2), 218-228. Retrieved from


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