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Jun 18, 2024
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Jun 18, 2024
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Abstract

In this study the drug corallocarpus epigaeus was evaluated for acute and chronic inflammation and the results of phytochemical studies shows the presence of alkaloids, carbohydrates, glycosides, tannins, flavonoids, fixed oils, saponins, proteins, steroids present in hydro alcoholic extract. The acute oral toxicity studies shows the LD50 value >2000 mg/kg. In carrageenan induced rat paw edema method the significant percentage inhibition of paw edema was obtained. The results obtained from the complete Freund’s Adjuvant induced arthritis model showed the significant inhibition of inflammation and there is no significant changes in biochemical and haematological parameters.

Keywords

Inflammation Percentage inhibition

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R. Sarojini, S. Selvakumar, & N. Chidambaranathan. (2024). Preclinical Evaluation of Hydro alcoholic extract of Corallocarpus epigaeus for Anti inflammatory activity. International Journal of Research in Pharmacology & Pharmacotherapeutics, 13(2), 176-202. Retrieved from https://ijrpp.com/ijrpp/article/view/549
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